Executive Director, Statistical Programming

4D Molecular Therapeutics

. Provide strategic and operational statistical programming leadership for assigned indications and development programs .

Posted 9/23/2026full-timeRemote • United StatesLead💰 $298,000 - $340,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates extensive expertise in statistical programming and biometrics leadership, with a strong focus on regulatory submissions and clinical trial standards. Proficient in SAS programming and experienced in managing programming teams and vendor oversight.

Highest-signal resume keywords

SAS Programming ExpertiseStatistical Programming LeadershipRegulatory Submissions ExperienceClinical Trial Standards KnowledgeManagement Experience

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

SAS/BASESAS MacrosSAS/STATSAS/GRAPHSAS/ACCESSRStatistical ProgrammingBiometricsData StandardsQuality Control

Soft Skills

CommunicationProject ManagementOrganizationInterpersonal SkillsAttention to Detail

Tools & Technologies

Microsoft OfficeSAS Server EnvironmentEDC DevelopmentCRF DevelopmentStatistical Computing Infrastructure

Industry Keywords

CDISCSDTMADaMCDASHMedDRAWHODrugGCPFDAICHHIPAA

Tech Stack

Tools & technologies

Google Cloud PlatformSQL

About the role

Key responsibilities & impact

Provide strategic and operational statistical programming leadership for assigned indications and development programs
Partner with biostatisticians and cross-functional stakeholders to review statistical analysis plans and develop data and analysis programming specifications
Ensure complete, auditable, inspection-ready programming documentation for clinical-trial analyses and regulatory submissions
Lead development, governance, documentation, and maintenance of reusable programming code, standards, templates, and best practices
Partner with IT and functional leadership to define and maintain statistical computing infrastructure, including the SAS server environment and related tools
Provide senior statistical programming expertise and biometrics leadership on selected projects and cross-functional initiatives
Collaborate on CRF/EDC development and quality data collection for assigned clinical trials
Oversee biometrics vendors and external programming partners, ensuring timely, high-quality deliverables, issue escalation, and accountability
Conduct or coordinate quality review of outsourced statistical deliverables, including in-house double programming or quality control as needed
Lead or contribute to function-level standards, SOPs, work instructions, templates, and continuous improvement initiatives
Monitor industry developments in biostatistics, statistical programming, regulatory expectations, automation, and data standards
Establish programming strategy, resource priorities, quality expectations, and risk mitigation plans, and communicate decisions and escalations to senior stakeholders
Perform other duties as assigned
Work in primarily sedentary conditions with typical office or administrative environmental exposure

Requirements

What you’ll need

A./B.S. degree in statistics, computer science, or another quantitative science major required
17+ years of relevant statistical programming, biometrics, or clinical development experience, including significant leadership experience in clinical development and regulatory submissions
Demonstrated experience leading statistical programming strategy and execution for regulatory submissions, including BLA/IND or equivalent global health authority submissions
8+ years of management experience, including scale-up of an in-house programming team
Expert SAS programming skills, including SAS/BASE, SAS Macros, SAS/STAT, and ODS
Proficiency in Microsoft Office applications, including Word, Excel, and PowerPoint
Strong understanding of clinical-trial standards, including CDISC, SDTM, ADaM, CDASH, MedDRA, and WHODrug
Knowledge of applicable GCP, FDA, CHMP, ICH, and HIPAA regulations
Less than 5% travel
Advanced degree preferred, or equivalent experience
Experience in ophthalmology and/or biologic/gene therapy a plus
Proficiency in SAS/SQL, SAS/GRAPH, SAS/ACCESS, R, Excel/PowerPoint Chart features, P21 checks, and experience across clinical phases I–IV are desirable or a plus
Strong organization, prioritization, time management, attention to detail, communication, analytical, strategic, interpersonal, vendor oversight, people leadership, and project management skills
Ability to identify risks and drive decision-making, escalation, and resolution
Sedentary work and repetitive wrist, hand, finger, typing, and speaking activities

Benefits

Comp & perks

Equal employment opportunities without regard to protected characteristics
Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities