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Absci

Director, Program Management

Absci

. Serve as the dedicated program management partner to a program leader across a portfolio of assets from discovery through IND and clinical entry .

Posted 10/23/2026full-timeUnited StatesLead💰 $185,000 - $210,000 per yearWebsite

Tech Stack

Tools & technologies
PMP

About the role

Key responsibilities & impact
  • Serve as the dedicated program management partner to a program leader across a portfolio of assets from discovery through IND and clinical entry
  • Build and maintain integrated, cross-functional development plans covering critical path, scope, timeline, and budget
  • Translate the AI-driven platform's design-build-test-learn cadence into executable, resourced plans
  • Extend planning into novel modalities, bespoke IND paths, and first-in-human transitions
  • Forecast and align program resources with functional leaders
  • Shape development strategy through scenario modeling, milestone forecasting, and resource trade-off analysis
  • Manage multiple CROs, CDMOs, and other external partners against scope, schedule, budget, and quality standards
  • Maintain escalation criteria and early-warning thresholds; raise risks with proposed mitigations
  • Adapt programs when priorities, data, timelines, or resources change
  • Prepare programs for stage-gate and governance reviews
  • Represent programs to executive leadership, governance committees, and alliance partners
  • Support evidence-based decisions, including recommendations to discontinue programs
  • Maintain portfolio dashboards and provide updates on status, spend, and cycle-time metrics
  • Improve program management standards, tools, and planning disciplines
  • Mentor program managers and serve as a change agent for planning and governance practices
  • Use agentic tools and multi-agent workflows to accelerate planning, analysis, and reporting

Requirements

What you’ll need
  • Bachelor's degree in a scientific, engineering, or technical discipline
  • 10+ years of professional experience in fast-paced biotech environments
  • 5+ years leading drug development programs
  • Equivalent combinations with an advanced degree will be considered
  • Track record of success in fast-paced biotech organizations
  • Experience managing drug development programs across discovery, preclinical, and IND-enabling stages
  • Exposure to clinical trial execution and regulatory submissions strongly preferred
  • Hands-on ownership of integrated development plans, critical-path management, budgets, and cross-functional resource planning across concurrent programs
  • Direct experience managing CRO and CDMO execution to schedule, budget, and quality
  • Ability to lead cross-functional teams and manage senior stakeholders, including executive leadership, governance committees, and alliance partners
  • Strong command of program management tools and practices, including MS Project, Smartsheet, portfolio dashboards, and scenario planning
  • Strong command of drug development processes and milestones
  • Hands-on experience with agentic AI tools, AI agents, and multi-agent workflows
  • Excellent written and verbal communication skills
  • Self-starter with sound judgment who thrives in ambiguity and operates autonomously in a fast-paced environment
  • Experience advancing antibody or other biologics programs from discovery through IND preferred
  • Experience partnering with AI, machine learning, or computational platform teams in drug discovery preferred
  • Experience in a small- to mid-cap or clinical-stage biotech, or rapidly scaling organization preferred
  • PMP, PgMP, or equivalent project/program management certification preferred
  • Familiarity with GxP requirements and clinical-stage quality expectations preferred
  • Direct experience managing clinical-stage programs preferred
  • Legal authorization to work in the United States is required

Benefits

Comp & perks
  • Equity
  • Bonus
  • Equal employment opportunity and non-discrimination
  • Reasonable accommodation during the hiring process and for essential job functions