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Senior Scientist, Mass Spectrometry
BeOne Medicines. Contribute creatively to Institute research by generating ideas, challenging assumptions, and advancing innovative scientific projects .
Posted 10/13/2026full-timeSan Carlos • California • United StatesSenior💰 $150,200 - $187,800 per yearWebsite
Core Competencies
Role fitCore Competencies
Use this summary to align your resume positioning with the role.
Demonstrates expertise in mass spectrometry techniques and workflows, with a strong focus on drug discovery and biological applications. Proven ability to analyze complex datasets and collaborate effectively with multidisciplinary teams.
Highest-signal resume keywords
Mass Spectrometry ExpertiseLC-MS Instrumentation OptimizationQuantitative ProteomicsData Analysis and InterpretationCollaborative Research Skills
ATS Keywords
Tailor your resumeApplicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills
Mass SpectrometryAnalytical ChemistryProteomics WorkflowsChromatography MethodsSample Preparation TechniquesData Acquisition SoftwareData Processing SoftwareDrug Discovery ResearchBiological ApplicationsPathway Interrogation
Soft Skills
Creative Problem SolvingStrong Communication SkillsLeadership AbilitiesCollaboration SkillsAttention to Detail
Tools & Technologies
Orbitrap SystemsAgilent Q-TOFsMS-Based Screening SoftwareAssay Development ToolsAnalytical Workflows
Industry Keywords
BiochemistryPharmaceutical SciencesCancer PathwaysCRO CollaborationASMS WorkflowsAPMS Workflows
About the role
Key responsibilities & impact- Contribute creatively to Institute research by generating ideas, challenging assumptions, and advancing innovative scientific projects
- Design and execute mass spectrometry-based studies addressing biological questions, emerging therapeutic modalities, and drug discovery
- Develop, optimize, and apply mass spectrometry-based screening, proteomics, and analytical workflows
- Support compound discovery, target identification, target engagement, mechanism-of-action studies, and pathway biology
- Evaluate and implement new mass spectrometry technologies, workflows, and applications
- Operate, maintain, troubleshoot, and improve mass spectrometry platforms
- Analyze, interpret, and communicate mass spectrometry data into biological and drug discovery insights
- Collaborate with multidisciplinary biology, chemistry, and related scientific teams
- Maintain high-quality experimental records and documentation
- Stay current with advances in mass spectrometry, analytical technologies, and related scientific fields
- Serve as a contact for external CRO partners when needed
- Provide matrix or line-function leadership for project teams when needed
Requirements
What you’ll need- Ph.D., M.S., or B.S. degree in Analytical Chemistry, Biochemistry, Biology, Chemistry, Pharmaceutical Sciences, or a related scientific discipline
- 2+ years of relevant industry, academic, or postdoctoral experience with a Ph.D.; 4+ years with an M.S.; or 5+ years with a B.S.
- Strong foundation in mass spectrometry
- Hands-on experience operating, troubleshooting, and optimizing LC-MS instrumentation
- Experience developing and implementing mass spectrometry-based analytical, screening, and/or proteomics workflows
- Demonstrated ability to apply mass spectrometry approaches to biological questions and drug discovery research
- Experience with quantitative proteomics and/or other MS-based approaches for protein identification, characterization, interaction analysis, or pathway interrogation
- Experience developing and optimizing sample preparation, chromatography, and mass spectrometry methods for biological applications
- Strong data analysis and interpretation skills involving complex mass spectrometry datasets
- Ability to troubleshoot analytical challenges and contribute creative solutions
- Ability to collaborate with scientists across biology, chemistry, and related disciplines
- Strong written, verbal, and presentation skills
- Ability to work on-site in San Carlos, CA
- Proficiency with mass spectrometry data acquisition, processing, and analysis software
- Strong computational and data analysis skills
- Experience with software and tools for MS-based screening and assay development
- Experience with Orbitrap systems (Astral a plus) and/or Agilent Q-TOFs
- Knowledge of cancer pathways
- Experience with ASMS and APMS workflows in a drug discovery setting a plus
Benefits
Comp & perks- Annual bonus plan eligibility for non-commercial roles
- Discretionary equity awards
- Voluntary participation in the Employee Stock Purchase Plan
- Medical insurance
- Dental insurance
- Vision insurance
- 401(k)
- FSA/HSA
- Life Insurance
- Paid Time Off
- Wellness benefits