Senior Director – Program Team Leader, Neurology and Pipeline Assets

. Own the integrated asset strategy, Target Product Profile, and development plan from IND-enabling work through proof of concept and beyond .

Posted 9/25/2026full-timeCambridge • Massachusetts • United StatesSenior💰 $307,000 - $325,350 per yearWebsite

Key responsibilities & impact

Own the integrated asset strategy, Target Product Profile, and development plan from IND-enabling work through proof of concept and beyond
Integrate clinical, regulatory, CMC, nonclinical, safety, commercial, and evidence-generation strategies into a coherent value-creation plan
Establish decision criteria, scenarios, and off-ramps for timely, evidence-based investment decisions
Maintain a current view of the scientific, competitive, and market landscape and translate it into program implications
Lead the cross-functional Program Team and create accountability for functional deliverables and overall program outcomes
Drive prioritization, resolve barriers, and secure resources for critical milestones, including DA02 IND submission and first-in-human readiness
Own the integrated timeline, budget, resource plan, and risk profile with Program Management and Finance
Ensure compliant, inspection-ready execution with high standards for scientific rigor, ethics, quality, and patient safety
Serve as the primary program voice to BlueRock executive and Board governance and Bayer stakeholders
Represent the asset externally with health authorities, investigators, key opinion leaders, patient organizations, and partners
Build alignment across BlueRock and Bayer and leverage partner capabilities
Contribute to portfolio strategy, capital allocation, long-range planning, and business development diligence
Capture and transfer program learning, tools, and standards across the portfolio

What you’ll need

Advanced degree (PhD, MD, PharmD) or equivalent combination of education and relevant experience
12+ years of progressive biotech or pharmaceutical drug development experience across multiple functions and development stages
5+ years leading global cross-functional program, product, or asset teams with accountability for outcomes
Demonstrated success advancing an asset through at least one major development transition, such as candidate selection to IND/CTA, first-in-human, proof of concept, or pivotal study initiation
Deep understanding of end-to-end development and the interdependencies across research, CMC/technical operations, nonclinical, clinical, regulatory, safety, and commercial disciplines
Direct development experience in neurology
Experience managing complex budgets, timelines, risks, and external development partners
Cell therapy, gene therapy, or other advanced therapy medicinal products, including allogeneic platforms
Rare disease, orphan, or expedited regulatory pathways
Surgically delivered or device-enabled therapies
Operating within a large-pharma partnership or lean biotech that leverages partner capabilities