Principal Scientist – Protein Engineering

Boehringer Ingelheim

. Lead and mentor a team of scientists, ensuring high standards of laboratory safety, data quality, and professional development .

Posted 11/12/2026full-timeVienna • AustriaLead💰 €90,900 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in therapeutic protein and antibody engineering, with a strong focus on design, optimization, and project leadership. Proven ability to lead multidisciplinary teams and translate biological insights into innovative therapeutic concepts.

Highest-signal resume keywords

PhD In Protein EngineeringTherapeutic Protein EngineeringMultispecific Antibody DesignComputational Protein DesignCross-Functional Collaboration

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Protein OptimizationAntibody Architecture UnderstandingData-Driven Protein EngineeringStructural ModelingBiophysical Data IntegrationBiochemical Data IntegrationFunctional Data IntegrationProject LeadershipCandidate SelectionTherapeutic Concepts Development

Soft Skills

Scientific JudgmentCommunication SkillsDecision-MakingSolution-Oriented LeadershipPositive Mindset

Tools & Technologies

AI/ML-Based ApproachesComputational ToolsLaboratory Safety StandardsData Quality Standards

Industry Keywords

BiotechnologyOncologyTherapeutic ProteinsComplex BiologicsExploratory Research

About the role

Key responsibilities & impact

Lead and mentor a team of scientists, ensuring high standards of laboratory safety, data quality, and professional development
Lead the design, engineering, and optimization of multispecific antibodies and other therapeutic proteins
Provide scientific and project leadership across portfolio projects
Manage multidisciplinary teams from exploratory research through candidate selection
Collaborate with Oncology scientists, internal experts, and external partners
Translate emerging biological insights into differentiated protein-based therapeutic concepts
Apply computational, structural, and data-driven protein engineering approaches
Optimize activity, selectivity, stability, expression, and developability
Drive projects from early-stage research through candidate selection

Requirements

What you’ll need

PhD in Protein Engineering, Biochemistry, Biotechnology, or a related field
Substantial postdoctoral and/or industry experience in therapeutic protein or antibody engineering
3–5 years of industry experience
Proven track record in the design and optimization of therapeutic proteins, ideally including multispecific antibodies or other complex biologics
Strong understanding of antibody architecture and protein structure-function relationships
Experience integrating sequence, biophysical, biochemical, and functional data to drive protein optimization
Familiarity with computational protein design, structural modeling, and AI/ML-based approaches is highly desirable
Ability to lead multidisciplinary discovery projects from exploratory research through candidate selection
Strong scientific judgment, communication skills, cross-functional collaboration, and effective decision-making in matrix organizations
Hands-on, solution-oriented leadership, ownership, positive and proactive mindset, and ability to deliver innovative therapeutic concepts through collaboration, agility, and operational excellence

Benefits

Comp & perks

Flexible working time models: home office and flexible working hours, depending on department and position
Additional days off (“bridge-days”)
Subsidized staff restaurant & cafeteria with vegetarian and vegan options
Diverse training and development opportunities
Health promotion programs for physical and mental health
Public transport ticket costs covered