Associate Director – Pharmacometrics

Bristol Myers Squibb

. Develop and implement the Model-Informed Drug Development (MIDD) strategy for drugs and therapeutic agents in clinical development .

Posted 11/12/2026full-timeUnited StatesSenior💰 $181,960 - $253,565 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in Model-Informed Drug Development (MIDD) and pharmacometrics, with a strong focus on quantitative data analysis, modeling, and regulatory decision-making. Proven ability to lead cross-functional initiatives and mentor junior scientists while effectively communicating complex scientific concepts.

Highest-signal resume keywords

Model-Informed Drug Development (MIDD)Pharmacometrics ExpertiseQuantitative Data AnalysisPopulation Pharmacokinetic (PPK) ModelingR, NONMEM, Monolix, MATLAB, Python

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Hard Skills

Quantitative Data AnalysisPopulation Pharmacokinetic (PPK) ModelingExposure-Response (E-R) ModelingMechanistic ModelingQuantitative Systems Pharmacology (QSP)Physiologically Based Pharmacokinetic (PBPK) Modeling

Soft Skills

Strong Written CommunicationStrong Verbal CommunicationInfluencing StakeholdersCollaborative Teamwork

Tools & Technologies

RNONMEMMonolixPumasMATLABPythonJulia

Industry Keywords

Clinical PharmacologyDrug Development ProcessRegulatory Decision-MakingHealth Authority Interactions

Tech Stack

Tools & technologies

Python

About the role

Key responsibilities & impact

Develop and implement the Model-Informed Drug Development (MIDD) strategy for drugs and therapeutic agents in clinical development
Partner with the Clinical Pharmacology lead to develop the MIDD strategy and define the PMx plan for assigned assets
Lead integration across quantitative disciplines to develop and execute a coherent modeling and data strategy
Plan, execute, interpret, and report formal PMx analyses supporting clinical study reports, health authority submissions, and regulatory responses
Translate complex modeling results into actionable recommendations informing asset strategy, development plans, and governance decisions
Serve as the MIDD subject matter expert and influence development decisions for therapeutic agents
Advance PMx infrastructure, tools, methodologies, and ways of working
Lead PMx and cross-functional initiatives strengthening quantitative decision-making across development programs
Provide scientific direction and oversight for PMx analyses conducted by external vendors
Represent the MIDD strategy and provide subject matter expertise in health authority interactions
Collaborate with internal and external subject matter experts to advance MIDD methodologies and capabilities
Provide scientific guidance and mentorship to junior scientists in PMx and MIDD

Requirements

What you’ll need

Advanced degree in a relevant scientific or quantitative field, such as an MS, PhD, or PharmD
5+ years of relevant experience with demonstrated progression in pharmacometrics and Clinical Pharmacology knowledge and increasing scientific impact
Expertise in quantitative data analysis, data wrangling and transformation, visualization, population pharmacokinetic (PPK) modeling, and exposure-response (E-R) modeling
Proficiency with relevant modeling and programming tools such as R, NONMEM, Monolix, Pumas, MATLAB, Python, and/or Julia
Working knowledge of the drug development process and applying quantitative evidence to development and regulatory decision-making
Experience with mechanistic modeling approaches such as Quantitative Systems Pharmacology (QSP) and Physiologically Based Pharmacokinetic (PBPK) modeling is preferred
In-depth knowledge of current practices, methodologies, and emerging issues in pharmacometrics and Clinical Pharmacology
Strong written and verbal communication skills
Ability to influence stakeholders and deliver compelling scientific presentations
Ability to translate complex modeling results into clear recommendations influencing cross-functional decisions
Proven ability to drive scientific impact in a dynamic, collaborative, and team-oriented environment

Benefits

Comp & perks

Comprehensive wellbeing support, retirement and financial protection benefits
Medical, dental, vision, life and disability insurance offerings
Flexible Time Off (FTO) for U.S.-based exempt employees, without a set accrual limit, subject to manager approval
11 paid company holidays annually
160 hours of paid vacation annually for eligible new hires
3 optional holidays for eligible non-exempt employees, RayzeBio employees, and employees located in Puerto Rico
Paid sick leave, subject to eligibility
Up to 2 paid volunteer days per year
Summer hours flexibility
Leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs
Annual Global Shutdown between Christmas Day and New Year's Day for eligible employees
Additional discretionary incentive cash and stock opportunities