Principal Scientist, Medical Physicist

Bristol Myers Squibb

. Apply radiopharmaceutical-specific modeling expertise to research and development of new drugs and therapies .

Posted 9/21/2026full-timeRemote • United StatesLead💰 $134,505 - $162,988 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in radiopharmaceutical dose modeling and analysis, with a strong background in molecular imaging and pharmacokinetic modeling. Proficient in utilizing advanced dosimetry software and statistical tools to support drug development and therapeutic applications.

Highest-signal resume keywords

Radiopharmaceutical Dose ModelingMolecular Imaging ExpertiseDosimetry Software ProficiencyCross-Functional CollaborationLeadership in Research Projects

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Radiopharmaceutical Dose ModelingMathematical Pharmacokinetic ModelingDosimetry CalculationsData AnalysisExperiment Design

Soft Skills

Creative Problem-SolvingClear CommunicationOrganizational SkillsTeam CoordinationProfessional Ethics

Tools & Technologies

3D-RD-SMIMMIRDcalcOLINDATorchGATESIMINDSAAM IISimBiologyPython

Certifications & Qualifications

PhD in Medical Physics or Engineering

Industry Keywords

RadiopharmaceuticalsAlpha-EmittersDosimetry GuidelinesClinical ImagingTherapeutics in Oncology

Tech Stack

Tools & technologies

Python

About the role

Key responsibilities & impact

Apply radiopharmaceutical-specific modeling expertise to research and development of new drugs and therapies
Perform radiopharmaceutical dose modelling and analyze in vitro and in vivo, clinical diagnostic, and therapeutic study data
Lead translational dosimetry analyses, including physiologically based pharmacokinetic and compartmentalization modelling
Provide technical support, dosimetry calculations, training, and problem-solving solutions to cross-functional teams
Collaborate with internal stakeholders, external vendors, and subject-matter experts
Support internal dosimetry analysis for discovery and development of radiopharmaceutical imaging and therapeutic agents
Design experiments and analyze dosimetric data from PET and SPECT imaging to assess drug uptake and distribution
Advise on best practices and standardization for image data quality control in preclinical research
Analyze preclinical and clinical imaging data to advance animal-to-human dose projection
Explore new technologies and modelling approaches, including novel radioisotopes such as alpha-emitters
Contribute to medical physics knowledge in radiopharmaceuticals
Apply AI to improve team execution and decision-making

Requirements

What you’ll need

Advanced degree in Medical Physics or Engineering with didactic training in RPT biodistribution, kinetics and dose modelling; PhD preferred
Minimum of 6 years of experience in molecular imaging and RPT dose modelling research, or 3 years of extensive RPT-specific publications (10+)
Experience with radiopharmaceuticals as therapeutics in oncology strongly desired
Experience with alpha-emitters strongly desired
Subject Matter Expert in mathematical pharmacokinetic modeling and its application in radiopharmaceutical research and development
Technical skills with dosimetry software, coding, and simulation/modeling/statistical tools, including 3D-RD-S, MIM, MIRDcalc, OLINDA, Torch, GATE, SIMIND, SAAM II, SimBiology, Python, Matlab, R, SPSS, ITK-snap, 3D slicer, and Elastix
Ability to communicate clearly and think creatively when problem-solving on multidisciplinary projects
Proven track record coordinating and aligning cross-functional stakeholders to deliver on corporate timelines in a team environment
Excellent communication skills and ability to present and discuss imaging and dosimetry topics clearly and concisely, including with scientific experts globally
Ability to organize, prioritize, and work effectively with minimal supervision in a constantly changing environment
Recognized leadership skills, professional ethics, integrity, and ability to maintain confidential information
Willingness to travel when needed (10–15%), including conference attendance that may involve evening and weekend work
Current knowledge of global dosimetry guidelines and passion for pioneering alpha-emitting radiotherapeutics a plus
Ability to meet physical demands, including occasionally lifting or moving up to 50 pounds

Benefits

Comp & perks

Additional discretionary incentive cash and stock opportunities
Wellbeing support
Retirement and financial protection benefits
Medical, dental, vision, life and disability insurance offerings
Flexible Time Off (FTO) without a set accrual limit for U.S.-based exempt employees
11 paid company holidays each year
160 hours of paid vacation annually for new hires for non-exempt employees, RayzeBio employees, and employees located in Puerto Rico
3 optional holidays for non-exempt employees, RayzeBio employees, and employees located in Puerto Rico
Paid sick leave, depending on eligibility
Up to two paid volunteer days per year, depending on eligibility
Summer hours flexibility
Leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs
Annual Global Shutdown between Christmas Day and New Year's Day for eligible employees
Reasonable workplace accommodations/adjustments and ongoing support for people with disabilities