Senior Director, Business Insights and Technology – Research, Clinical Pharmacology & Pharmacometrics

Bristol Myers Squibb

. Serve as the single BI&T point of accountability for CPP technology, applications, workflows, and support services end to end .

Posted 11/11/2026full-timeUnited StatesSenior💰 $229,670 - $306,137 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in leading the development and execution of CPP technology strategies, ensuring compliance and operational excellence in scientific workflows. Proficient in managing cross-functional partnerships and building specialized teams to drive innovation in clinical pharmacology and pharmacometrics.

Highest-signal resume keywords

Ph.D. In Pharmacometrics12+ Years In Pharmaceutical R&DExperience With NONMEM, Monolix, R, PythonDirector-Level Leadership ExperienceExperience Supporting Regulatory Submissions

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Hard Skills

PharmacometricsClinical PharmacologyQuantitative Workflow AutomationModel-Informed Drug DevelopmentAI/ML ApplicationMLOpsQuantitative ReportingHPC/Cloud ComputeData EngineeringSoftware-Delivery Practices

Soft Skills

Team LeadershipCollaborationChange ManagementTalent DevelopmentCommunication

Tools & Technologies

PBPK/QSP PlatformsCPP ApplicationsClinical PK/PD SystemsContainerized ToolchainsReproducible Analysis Workspaces

Industry Keywords

Regulatory ComplianceScientific ComputingOperational SupportTranslational ScienceMatrixed Organizations

Tech Stack

Tools & technologies

CloudPython

About the role

Key responsibilities & impact

Serve as the single BI&T point of accountability for CPP technology, applications, workflows, and support services end to end
Define and own the multi-year CPP technology strategy, architecture, and product roadmap
Partner across Research and Development to integrate CPP workflows with scientific, data, and operational capabilities
Own the lifecycle of CPP applications, modeling environments, scientific-computing infrastructure, reporting pipelines, and operational support, including build/buy/partner decisions
Ensure operational excellence, reliability, governance, and continuous improvement across modeling environments, clinical PK/PD systems, reporting workflows, and submission-support applications
Lead engineering delivery of workflow automation for model execution, simulation, reporting, traceability, review workflows, and evidence reuse
Own validation and compliance for regulated CPP systems with Quality, Regulatory, and IT Compliance
Partner with Unified Lab & Experimental Platforms, Target & Disease Biology, and In-Vivo & Non-Clinical Pharmacology on intersecting translational science and platform needs
Partner with R&D Data on data-product strategy, integration, and fit-for-purpose data access
Lead and grow a team of scientific technologists, product leaders, and specialized engineers
Provide scalable application and workflow infrastructure for CPP modeling and simulation, preclinical-to-clinical translation, dose selection, and model-informed development decisions
Deliver scientific-computing and modeling environments using HPC/cloud compute, containerized toolchains, and reproducible analysis workspaces
Strengthen regulatory submissions through reusable quantitative evidence generation and auditable outputs
Enable governed agentic-AI automation across reporting, modeling and simulation, execution, review, and knowledge reuse
Build a durable, integrated technology foundation for end-to-end CPP workflows

Requirements

What you’ll need

Advanced degree in Pharmacometrics, Clinical Pharmacology, Pharmaceutical Sciences, Biostatistics, or related quantitative field; Ph.D. preferred
12+ years of experience in pharmaceutical R&D or life-sciences technology, with substantial experience in technology, informatics, or platform leadership supporting clinical pharmacology, pharmacometrics, or model-informed drug development
Hands-on familiarity with NONMEM, Monolix, R, Python, and PBPK/QSP platforms
Experience implementing or leading CPP applications, PBPK and QSP environments, clinical PK/PD systems, or quantitative workflow automation
Experience supporting regulatory submissions, quantitative reporting, and governed Development-facing workflows
Experience applying AI/ML, LLM-based tooling, or advanced automation to quantitative modeling, reporting, or regulated scientific workflows, including MLOps and model governance considerations (preferred)
Director or Senior Director-level leadership experience
Experience building and scaling a specialized scientific technology team is a strong differentiator
Scientific fluency in clinical pharmacology and pharmacometrics
Fluency in cloud, HPC, data engineering, and software-delivery practices
Experience with product management, roadmaps, prioritization, and outcome metrics
Experience leading technology modernization and change management in scientific user communities
Ability to recruit, develop, and retain specialized quantitative talent
Experience navigating matrixed organizations
Experience partnering with senior scientific, clinical, and regulatory leaders
Comfort operating with regulatory and global Development stakeholders

Benefits

Comp & perks

Comprehensive benefits including wellbeing support, retirement and financial protection benefits, and medical, dental, vision, life and disability insurance
Flexible Time Off (FTO) for eligible U.S.-based exempt employees
11 paid company holidays each year
160 hours of paid vacation annually for eligible non-exempt employees, RayzeBio employees, and employees in Puerto Rico
3 optional holidays for eligible non-exempt employees, RayzeBio employees, and employees in Puerto Rico
Paid sick leave, subject to eligibility
Up to two paid volunteer days per year
Summer hours flexibility
Medical, personal, parental, caregiver, bereavement, or military leaves of absence
Annual Global Shutdown between Christmas Day and New Year's Day for eligible employees
Additional discretionary incentive cash and stock opportunities may be available
Reasonable workplace accommodations/adjustments and ongoing support for people with disabilities