Senior Research Investigator, Pharmacometrics

Bristol Myers Squibb

. Develop and implement model-informed drug development (MIDD) plans for drugs and other therapeutic agents in clinical development .

Posted 11/12/2026full-timeUnited StatesSenior💰 $146,420 - $204,043 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in model-informed drug development (MIDD) and pharmacometrics, with strong capabilities in quantitative data analysis, programming, and collaboration with cross-functional teams. Proficient in advanced pharmacokinetic and exposure-response analysis, contributing to regulatory submissions and health authority interactions.

Highest-signal resume keywords

Model-Informed Drug Development (MIDD)Pharmacometrics AnalysisProgramming Experience with R, NONMEM, Monolix, Pumas, Matlab, Python, JuliaAdvanced Pharmacokinetic (PPK) AnalysisData Visualization

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Quantitative Data AnalysisData WranglingAdvanced Exposure-Response AnalysisMechanistic ModelingScientific Machine Learning

Soft Skills

Strong Written CommunicationStrong Oral CommunicationTeam-Oriented Collaboration

Certifications & Qualifications

Advanced Degree (MS, PhD, PharmD)

Industry Keywords

Clinical DevelopmentHealth Authority SubmissionsPharmacologyDrug Development ProcessCurrent Practices in Pharmacometrics

Tech Stack

Tools & technologies

Python

About the role

Key responsibilities & impact

Develop and implement model-informed drug development (MIDD) plans for drugs and other therapeutic agents in clinical development
Partner with Clinical Pharmacology leads and other quantitative functions on asset modeling and data plans
Plan, execute, and report formal pharmacometrics analyses for CSRs, health authority submissions, and responses to health authority questions
Serve as a MIDD subject-matter expert in therapeutic-agent development
Maintain and refine pharmacometrics infrastructure
Contribute to PMx and cross-functional initiatives
Manage pharmacometrics analyses performed by vendors
Participate in health authority interactions as a MIDD subject-matter expert
Collaborate with internal and external subject-matter experts to develop and enhance MIDD methodology and capability
Integrate diverse data through pharmacometrics models to generate insights, bridge data gaps, and inform drug development decisions and regulatory assessments

Requirements

What you’ll need

Advanced degree(s) in a relevant field: MS, PhD, or PharmD
2+ years' experience with demonstrated progression in PMx and CP knowledge
Basic quantitative data analysis
Data wrangling, including merging and transforming data
Data visualization
Advanced PPK and exposure-response analysis
Programming experience with R, NONMEM, Monolix, Pumas, Matlab, Python, and Julia
General knowledge of the drug development process
Knowledge of current practices and issues in PMx and CP
Strong written and oral communication skills
Demonstrated ability to work in a dynamic, team-oriented environment
Local and international travel for conferences and regulatory meetings may be required, up to 5–10% of the time
Knowledge of mechanistic modeling is desired
Understanding of modern PMx approaches such as QSP, PBPK, scientific machine learning, and agentic workflows is a significant bonus

Benefits

Comp & perks

Comprehensive wellbeing support, retirement and financial protection benefits
Medical, dental, vision, life and disability insurance offerings
Flexible Time Off (FTO) without a set accrual limit for eligible U.S.-based exempt employees
11 paid company holidays annually
160 hours of paid vacation annually for eligible new hires
3 optional holidays for eligible employees
Paid sick leave
Up to two paid volunteer days per year
Summer hours flexibility
Medical, personal, parental, caregiver, bereavement, or military leaves of absence
Annual Global Shutdown between Christmas Day and New Year's Day
Additional discretionary incentive cash and stock opportunities
Workplace accommodations/adjustments and ongoing support
Opportunities for growth and a supportive, inclusive work environment