R&D Engineer II

Chan Zuckerberg Initiative

. Design, build and test prototypes for point-of-care sample processing, iterating based on performance data and optimizing for reproducibility .

Posted 9/28/2026full-timeNew York City • New York • United StatesMid-LevelSenior💰 $153,000 - $191,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in designing and optimizing point-of-care medical devices, with a strong foundation in engineering principles, biological sample handling, and experimental design. Proficient in CAD and rapid prototyping techniques to drive project success and ensure reproducibility.

Highest-signal resume keywords

Biomedical EngineeringPoint-Of-Care Device DevelopmentCAD Proficiency3D PrintingExperimental Design

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Biological Sample HandlingAssay ValidationDevice EngineeringMaterials Science KnowledgeTest Protocol EstablishmentPrototype TestingTroubleshooting Complex WorkflowsDocumentationProject ManagementPerformance Optimization

Soft Skills

Collaborative MindsetScientific Communication

Certifications & Qualifications

Bachelor's Degree in EngineeringMaster’s Degree in Engineering

Industry Keywords

Diagnostic DevicesPoint-Of-Care TestingRapid PrototypingBiochemical ProcessesReproducibility

About the role

Key responsibilities & impact

Design, build and test prototypes for point-of-care sample processing, iterating based on performance data and optimizing for reproducibility
Design mechanisms for controlled timing and sequencing of biochemical processes within a device, such as controlled reagent release and passive valving
Perform hands-on preparation and handling of biological specimens and conduct assay validation experiments
Apply device engineering, cell biology, and materials science knowledge to hardware design decisions
Establish test protocols and acceptance criteria for reproducible performance across prototype iterations and production lots
Participate in discussions with project collaborators
Carefully document work
Clearly report on project progress
Contribute to scientific publications and patent applications

Requirements

What you’ll need

Bachelor's or Master’s Degree in Engineering, especially biomedical, chemical or mechanical engineering, plus 5+ years of relevant, post-graduate hands-on engineering experience
Holders of non-engineering degrees must have at least 6 years of hands-on engineering experience developing hardware
Track record of developing diagnostic or point-of-care medical devices
Experience with handling biological samples
Proficiency in CAD
Experience with 3D printing and rapid prototyping
Ability to independently design rigorous experiments, troubleshoot complex workflows, and drive projects to completion
Strong documentation habits
Collaborative mindset and strong scientific communication skills

Benefits

Comp & perks

Discretionary annual performance bonus program eligibility
Generous employer match on employee 401(k) contributions
Paid time off to volunteer at an organization of your choice
Funding for select family-forming benefits
Relocation support for employees who need assistance moving