Director, Data Management

Climb Bio

. Design and build clinical database architecture for clinical studies, including edit checks, structures, and specifications .

Posted 10/6/2026full-timeWellesley • Massachusetts • United StatesSeniorWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates extensive expertise in clinical data management, including database architecture design, user acceptance testing, and vendor management. Proficient in establishing data management standards and ensuring compliance with regulatory requirements.

Highest-signal resume keywords

Clinical Data ManagementDatabase Architecture DesignUser Acceptance Testing (UAT)CRO ManagementGood Clinical Practice (GCP)

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Database DesignData CleaningQuery ResolutionReconciliation ActivitiesData Management StandardsSOP DevelopmentTimeline ManagementPerformance OversightRegulatory ComplianceData Quality Management

Soft Skills

Cross-Functional CollaborationProblem SolvingLeadershipCommunicationAccountability

Tools & Technologies

Clinical Database PlatformsElectronic Data Capture (EDC) Systems

Industry Keywords

Clinical StudiesBiostatisticsClinical OperationsData Management CROsPhase 3 Database Lock

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Design and build clinical database architecture for clinical studies, including edit checks, structures, and specifications
Own end-to-end user acceptance testing for clinical database builds, from test plan development through final sign-off
Manage data management timelines and deliverables across clinical studies
Hold vendors accountable to milestones from first patient in through database lock
Direct selection and ongoing performance oversight of data management CROs and vendors
Serve as primary escalation point for data quality and timeline issues
Partner with Biostatistics, Clinical Operations, and Regulatory to align data management plans, CRF design, and database specifications with study protocols
Establish data management standards, SOPs, and quality control processes
Lead data cleaning, query resolution, and reconciliation activities
Represent Data Management in cross-functional program governance and report on database timelines, risks, and trade-offs

Requirements

What you’ll need

Bachelor's degree in life sciences or a related field
10+ years of clinical data management experience (12+ years for Director-level candidates)
Experience taking a database through Phase 3 database lock
Experience designing clinical databases
Experience leading user acceptance testing (UAT) execution
Experience managing CRO and data management vendor relationships, including performance oversight
Working knowledge of GCP and applicable regulatory requirements for clinical data management
Preferred: Experience in a small, fast-paced biotech environment
Preferred: Proficiency with industry-standard clinical database and EDC platforms

Benefits

Comp & perks

Discretionary annual bonus
Comprehensive medical, dental, and vision benefits
Life and disability insurance
401(k) company match
Generous paid time off
Equity