Medical Director, Medical Affairs

COMPASS Pathways

. Serve as a medical subject matter expert in treatment-resistant depression, interventional psychiatry, and emerging psychiatric treatments .

Posted 10/31/2026full-timeRemote • United StatesLead💰 $270,000 - $320,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in treatment-resistant depression and interventional psychiatry, with a strong foundation in clinical research methodology and evidence-based medicine. Capable of providing medical oversight for research initiatives and effectively communicating complex findings to diverse audiences.

Highest-signal resume keywords

MD Or DO DegreeClinical Research MethodologyTreatment-Resistant Depression ExpertiseMedical Affairs ExperienceBoard Certification In Psychiatry

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical ResearchScientific CommunicationData InterpretationEvidence-Based MedicineResearch Proposal DevelopmentClinical Protocol DevelopmentReal-World Evidence StudiesMedical OversightAdvisory Board LeadershipInterventional Psychiatry

Soft Skills

Effective CommunicationStakeholder EngagementMultidisciplinary CollaborationProject ManagementCritical Evaluation

Certifications & Qualifications

Board Certification In Psychiatry

Industry Keywords

Emerging Psychiatric TreatmentsMedical AffairsClinical TrialsPharmaceutical DevelopmentRegulatory RequirementsScientific PublicationsTherapeutic Area EducationMedical Review ProcessesClinical DevelopmentPsychedelic Therapeutics

About the role

Key responsibilities & impact

Serve as a medical subject matter expert in treatment-resistant depression, interventional psychiatry, and emerging psychiatric treatments
Provide clinical insights and recommendations to inform Medical Affairs priorities and initiatives
Evaluate clinical trial results, scientific literature, and treatment guidelines to inform medical strategy and decision-making
Partner with Scientific Communications, Medical Information, Medical Education, and Field Medical leadership
Identify clinical developments and practice considerations for future Medical Affairs priorities
Provide medical expertise for future therapeutic indications and pipeline opportunities
Lead Medical Affairs research proposals and evidence-generation initiatives
Collaborate on research concepts, protocols, and analysis plans
Provide medical oversight for sponsored research, real-world evidence studies, observational research, and post-approval evidence generation
Evaluate investigator-initiated research proposals and external research collaborations
Interpret and disseminate findings through publications and congress presentations
Lead or contribute to advisory boards, expert consultations, congresses, and professional society meetings
Engage external experts regarding clinical evidence, treatment practices, and novel psychiatric interventions
Support scientific exchange, therapeutic area education, and field medical insight interpretation
Support publications, scientific presentations, medical education materials, and Medical Information resources
Serve on the Medical, Legal, and Regulatory review committee
Review scientific claims, clinical data, and medical content for accuracy, balance, relevance, and evidence consistency
Collaborate with Regulatory, Legal, Compliance, Clinical Development, Clinical Sciences, Safety, HEOR, and other functions
Support responses to complex scientific inquiries from healthcare professionals
Reports to the Executive Director, Medical Affairs

Requirements

What you’ll need

MD or DO degree from an accredited medical institution
Clinical training and demonstrated expertise in psychiatry
Strong knowledge of treatment-resistant depression and contemporary psychiatric treatment approaches
Experience in clinical research, academic medicine, pharmaceutical development, Medical Affairs, or a related scientific or clinical setting
Ability to critically evaluate clinical research, interpret complex data, and communicate findings to diverse medical and scientific audiences
Experience contributing to clinical research, scientific publications, medical education, or other evidence-generation activities
Strong understanding of clinical research methodology, evidence-based medicine, and scientific communication
Ability to engage effectively with senior medical and scientific stakeholders
Ability to manage multiple initiatives and work effectively across multidisciplinary teams
Employment rights in the country to which you are applying; employment visa sponsorship is unavailable
Preferred: Board certification in Psychiatry
Preferred: Experience in interventional psychiatry, including esketamine, ketamine, transcranial magnetic stimulation, electroconvulsive therapy, or psychedelic therapeutics
Preferred: Prior pharmaceutical or biotechnology Medical Affairs, Clinical Development, or related industry experience
Preferred: Experience developing research proposals, clinical protocols, real-world evidence studies, or investigator-initiated research programs
Preferred: Established relationships within psychiatry, particularly in TRD, interventional psychiatry, or emerging psychiatric therapeutics
Preferred: Experience leading scientific advisory boards, expert consensus initiatives, or external scientific collaborations
Preferred: Familiarity with pharmaceutical medical review processes, MLR governance, and regulatory requirements governing scientific communications
Preferred: Experience supporting late-stage clinical development, product launch preparation, or early commercialization activities

Benefits

Comp & perks

Base salary, discretionary bonus, and equity
Flexibility and generous time off
Parental and reproductive support
Health and medical benefits
Mental health and wellbeing support
Financial health benefits
Reasonable accommodation during the interview process