Clinical Program Manager

Encoded Therapeutics Inc.

. Lead the operational strategy and execution for a novel clinical-stage gene therapy program .

Posted 10/27/2026full-timeRemote • United StatesMid-LevelSenior💰 $145,000 - $180,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates extensive experience in managing complex clinical trials, particularly in gene therapy, with a strong understanding of FDA and ICH guidelines, GCP, and clinical protocol design. Proven ability to lead cross-functional teams, manage budgets, and ensure compliance with regulatory requirements.

Highest-signal resume keywords

Clinical Operations ManagementGene Therapy ExperienceProject ManagementRegulatory ComplianceBudget Management

ATS Keywords

Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills

Clinical Trial ManagementProtocol DevelopmentRisk Mitigation StrategiesClinical Study DocumentationData Review ActivitiesTrial Master File MaintenanceVendor ManagementFinancial AcumenClinical Protocol DesignDrug Development Knowledge

Soft Skills

Problem-Solving AbilitiesOrganizational SkillsInterpersonal SkillsCollaboration SkillsWritten Communication Skills

Tools & Technologies

Word Processing SystemsSpreadsheet SystemsDatabase SystemsPresentation SystemsFiling Systems

Industry Keywords

Clinical TrialsGood Clinical Practices (GCP)FDA RequirementsINDsCTAsMedical TerminologyInternational RegulationsEnrollment GoalsStudy Management PlansCross-Functional Initiatives

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Lead the operational strategy and execution for a novel clinical-stage gene therapy program
Manage end-to-end operational execution from protocol concept through Clinical Study Report completion
Drive cross-functional alignment, trial budgets, and project timelines
Develop clinical study documents and procedures, including protocols, informed consent forms, investigator brochures, case report forms, and study procedure manuals
Identify and interpret risks and implement mitigation strategies and corrective actions
Develop and manage clinical study timelines and budgets
Select study investigators and evaluate their research capabilities and ability to meet timelines
Build relationships with clinical sites and manage studies to meet enrollment goals
Contribute to INDs, CTAs, and other regulatory documents
Conduct oversight monitoring activities as needed
Partner with data management colleagues to lead study data review activities
Oversee ongoing Trial Master File maintenance
Contribute to clinical study reports
Monitor compliance with company SOPs, GCP, FDA requirements, and applicable international regulations
Create and implement Study Management plans and processes
Represent clinical operations in cross-functional initiatives and act on behalf of the team as assigned
Provide direct line management, oversight, and operational guidance to contract Clinical Operations personnel
Report to the Senior Director of Clinical Operations

Requirements

What you’ll need

Minimum of 8 years of pharma/biotech clinical operations experience with a Bachelor’s degree in a relevant scientific discipline or equivalent (6 years with a Master’s, or 3 years with a PhD)
Proven end-to-end management of complex clinical trials; gene therapy experience strongly preferred
Thorough knowledge and understanding of FDA and ICH Guidelines, Good Clinical Practices (GCP), medical terminology, and clinical trials
Detailed understanding of clinical protocol design and implementation and overall drug development
Outstanding project management experience
History of success selecting and managing vendors with performance standards
Strong financial acumen, including building budgets and managing expenses to budget
Proficiency with word processing, spreadsheet, database, presentation, and filing (archiving) systems
Demonstrated problem-solving abilities and strong organizational skills
Outstanding written communication skills, including writing technical trial documents
Ability to self-motivate, prioritize and manage a large volume of work, and demonstrate attention to detail
Strong interpersonal and collaboration skills
Excellent verbal and written communication skills
Ability to travel internationally and domestically as required

Benefits

Comp & perks

Comprehensive benefits package, including competitive employer premium contributions
Meaningful stock option grants
PTO, sick time and holiday pay
Generous Parental Leave program
Pre-tax medical and dependent care programs
STD, LTD, Life and AD&D
Professional development opportunities
Team-building events
Fully stocked micro - kitchen
Fitness center at South San Francisco location
Discretionary annual bonus
Discretionary stock-based long-term incentives