SVP Clinical Development – Global Program Lead, Pancreatic Cancer

Erasca, Inc.

. Provide medical leadership and oversight for pancreatic and colorectal cancer development programs .

Posted 9/24/2026full-timeRemote • California • United StatesSenior💰 $390,000 - $435,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in oncology clinical trial design and execution, with a strong focus on regulatory compliance and strategic leadership. Proven ability to collaborate across functions and mentor clinical teams while maintaining a commitment to scientific integrity and patient outcomes.

Highest-signal resume keywords

M.D. DegreeOncology Clinical Trial ExperienceRegulatory Filing ExperienceClinical Development LeadershipExecutive Leadership Skills

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Trial MethodologyClinical Study DesignData InterpretationRegulatory SubmissionsSafety Profile AssessmentClinical Research ProtocolsIND AuthoringNDA AuthoringEfficacy Data CommunicationScientific Publication

Soft Skills

Interpersonal SkillsCommunication SkillsInfluencing SkillsWriting SkillsCollaboration Skills

Certifications & Qualifications

Board Certification in OncologyBoard Certification in Oncology/Hematology

Industry Keywords

Pancreatic CancerColorectal CancerGI CancersPharmaceutical IndustryBiotechnology IndustryHealth Authority InteractionClinical Development SubteamDue DiligenceBusiness DevelopmentMatrixed Team Environment

About the role

Key responsibilities & impact

Provide medical leadership and oversight for pancreatic and colorectal cancer development programs
Collaborate with the Chief Medical Officer across the Erasca portfolio
Lead the clinical development subteam for all GI cancer studies
Design and implement novel, efficient clinical trials and assess appropriate endpoints
Lead clinical study subteams and monitor study integrity
Review, interpret, and communicate safety and efficacy data
Develop registrational strategies and contribute to regulatory filings and health authority interactions
Author clinical sections for INDs, NDAs, and related documents
Serve as medical lead and/or medical monitor on clinical programs and individual studies
Partner with Drug Safety to assess compound safety profiles
Author or support medical aspects of clinical research plans, protocols, investigator brochures, clinical study reports, and regulatory submissions
Contribute to scientific publications and author manuscripts
Present at scientific, medical, and regulatory meetings
Maintain clinical and scientific expertise through literature review and engagement with thought leaders, investigators, stakeholders, and partners
Participate in due diligence and business development activities
Hire, develop, and mentor medical directors and clinical scientists
Establish and maintain relationships across Erasca, particularly with Research and Development partners and stakeholders
Perform duties in accordance with company values, policies, and applicable regulations

Requirements

What you’ll need

M.D. degree or equivalent, with subspecialty fellowship training and board certification or eligibility in Oncology or Oncology/Hematology required
8-10+ years of oncology clinical trial and drug development experience, including extensive experience in the pharmaceutical or biotechnology industry
Experience as the clinical lead on late-stage clinical programs in colorectal, pancreatic, or other GI cancers required
Experience leading or being closely involved in the clinical aspects of a regulatory filing and direct interaction with health authorities required
Exposure to early development and the transition from FIH to registrational trials preferred
Extensive knowledge of clinical trial methodology and regulatory and compliance requirements governing clinical trials
Demonstrated ability to collaborate successfully with multiple functions in a matrixed team environment
Executive leadership skills to educate and influence stakeholders and contribute to strategic business planning and decision-making
Effective interpersonal, communication, influencing, and excellent writing skills
Ability to achieve high performance goals and meet deadlines in a fast-paced environment
Strong learning orientation, curiosity, and commitment to science and patients

Benefits

Comp & perks

Annual bonus
Equity grant at hire and annually in the form of an option to purchase stock in the future for a specified price
Paid Time Off
Holiday and Sick Leave
Medical, Dental and Vision Plans
Short- and Long-Term Disability
Basic and Voluntary Life/AD&D Coverage
Flexible Spending Accounts (FSA, HSA, and Commute)
Critical Illness and Accident Coverage
Pet Insurance
Employee Assistance Program
401(k) Plan with Erasca contribution
Employee Stock Purchase Program
Casual, collaborative, and fun work environment