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Freenome

Staff Software Engineer

Freenome

. Lead the design, development, and operation of maintainable, scalable, and reliable backend software .

Posted 11/5/2026full-timeRemote • California • United StatesLead💰 $188,275 - $270,375 per yearWebsite

Core Competencies

Role fit
Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in backend software design and development, with a strong focus on building scalable systems and data integrations. Proficient in Python and SQL, with experience in cloud platforms and containerization technologies, while fostering collaboration and mentoring within cross-functional teams.

Highest-signal resume keywords
Backend Software DevelopmentPython ProficiencySQL ProficiencyContainerization with Docker and KubernetesInfrastructure as Code on Cloud Platforms

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills
Backend Software DevelopmentPython ProficiencySQL ProficiencyDistributed SystemsData Pipeline DevelopmentData Quality ValidationSoftware Architecture LeadershipClean Code PracticesAnalytical Data ModelingAccess Control Implementation
Soft Skills
Excellent Communication SkillsCollaborationMentoringTeam Growth FacilitationCross-Functional Teamwork
Tools & Technologies
DockerKubernetesAzureGoogle CloudApache ParquetApache IcebergFlyteAirflowAI ToolsReal World Data Workflows
Industry Keywords
Life SciencesReal World DataFDA-Regulated EnvironmentData CurationData Integration

Tech Stack

Tools & technologies
AirflowApacheAzureCloudDistributed SystemsDockerKubernetesPythonSQL

About the role

Key responsibilities & impact
  • Lead the design, development, and operation of maintainable, scalable, and reliable backend software
  • Build system and data integrations connecting commercial products and external providers with analytical platforms
  • Enable feedback loops that accelerate research and product development
  • Work with TPMs and SMEs to understand business needs and translate product requirements into technical strategy and incremental execution
  • Partner with the Real World Data team to evolve its technology stack and identify workflow bottlenecks
  • Build reusable tools for data curation and analysis
  • Use AI tools to scale engineering and Real World Data workflows, automate manual operations, reduce data curation efforts, and improve data quality
  • Evaluate technologies, frameworks, and data providers through focused proofs of concept
  • Lead code and design reviews and champion engineering best practices
  • Promote a culture of quality and collaboration
  • Contribute to hiring and mentoring new team members
  • Foster team growth and enhance technical knowledge and productivity
  • Partner with product managers, clinical data analysts, informaticists, researchers, and external vendors
  • Report to the Director of Engineering, Platform

Requirements

What you’ll need
  • Bachelor of Science in Computer Science, Engineering, or related field or equivalent work experience
  • 10+ years as a software engineer successfully shipping software in production, preferably in backend or platform teams
  • 2+ years as a lead developer
  • Proficiency in Python and SQL
  • Ability to build and operate distributed systems using Infrastructure as Code on public cloud platforms, preferably Azure or Google Cloud
  • Expertise developing and running containerized software, preferably using Docker and Kubernetes
  • Track record of building and operating data pipelines and integrations, including ingestion, database replication, analytical data modeling, or data quality validation
  • Experience building systems that process and store sensitive data such as PHI, implementing access controls, audit logging, and secure data handling
  • Software architecture leadership, including clean code, design documents and ADRs, constructive reviews, and collaborative technical decisions
  • Excellent written and verbal communication skills
  • Ability to thrive in cross-functional, collaborative environments
  • Domain-specific experience or academic background in life sciences, real world data, or related fields (nice to have)
  • Experience working in an FDA-regulated environment (nice to have)
  • Experience with Apache Parquet (nice to have)
  • Experience with open lakehouse technologies and Apache Iceberg (nice to have)
  • Experience with Flyte, Airflow, or similar workflow orchestration frameworks (nice to have)
  • Experience with scientific Python frameworks and data-science tools (nice to have)

Benefits

Comp & perks
  • Equity
  • Cash bonuses
  • Full range of medical benefits
  • Financial benefits
  • Other benefits depending on the position offered
  • Remote work within the US
  • Occasional travel to headquarters only 2–3 times a year