Senior Software Engineer - Commercial

GRAIL

. Design, build, and operate backend services and distributed systems powering GRAIL's commercial offerings for the Galleri® test, including my.grail.com and provider.grail.com .

Posted 10/13/2026full-timeSunnyvale • California • United StatesSenior💰 $169,000 - $204,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in designing, building, and maintaining backend services and distributed systems, with a strong focus on cloud platforms and healthcare compliance. Proficient in programming languages and frameworks, with a commitment to improving software quality and team collaboration.

Highest-signal resume keywords

Backend Programming Languages (Go, Java, Python, C++)Cloud Platform Experience (AWS, GCP, Azure)React Application DevelopmentMicroservice Architecture DesignHealthcare Software Compliance (HIPAA, PHI)

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Backend Programming LanguagesProduction Application DevelopmentAutomated Testing StrategiesMicroservice ArchitectureRelational Databases (PostgreSQL, MySQL)Infrastructure as Code (Terraform)Containerization (Kubernetes, Docker)CI/CD PipelinesGRPC-based Service CommunicationObservability and Reliability Tooling

Soft Skills

Strong Written and Verbal CommunicationMentorshipJudgment and Decision-MakingCollaboration with StakeholdersAdaptability

Tools & Technologies

AWSGCPAzureTerraformKubernetesDockerRedisCI/CD ToolsAutomated Testing ToolsObservability Tools

Industry Keywords

Healthcare SoftwareRegulated DomainSoftware QualityValidation RequirementsPHI Handling

Tech Stack

Tools & technologies

AWSAzureCloudDistributed SystemsDockerGoogle Cloud PlatformGRPCJavaKubernetesMySQLPostgresPythonReactRedisTerraformC++Go

About the role

Key responsibilities & impact

Design, build, and operate backend services and distributed systems powering GRAIL's commercial offerings for the Galleri® test, including my.grail.com and provider.grail.com
Own features and services end to end, from technical design through implementation, testing, deployment, and production support
Build and maintain React interfaces used by patients, clinicians, and internal clinical operations teams
Lead technical design of projects of diverse scope and bring designs forward for review
Devise solutions where precedent is limited and exercise judgment to select the right course of action
Partner with product managers, clinical operations, and engineering teams to turn ambiguous requirements into technical plans
Advise senior stakeholders and adapt communication to the audience
Write and maintain automated tests and test protocols for software operating in a regulated healthcare environment
Improve reliability and observability of owned systems
Participate in on-call rotation, incident response, and follow-up remediation
Raise engineering quality through code review, pairing, and mentorship
Drive improvements to tooling, CI/CD pipelines, and development practices

Requirements

What you’ll need

Bachelor's degree in Computer Science, Electrical Engineering, Bioinformatics, or a similar technical field with 5+ years of related experience, or a Master's degree with 2+ years of related experience, or a PhD, or equivalent experience
Professional experience designing, developing, testing, and maintaining production backend or full-stack applications
Professional experience building and operating services on a major cloud platform such as AWS, GCP, or Azure
Proficiency in at least one backend programming language such as Go, Java, Python, or C++
Strong professional written and verbal communication skills
Experience writing production Go and with gRPC-based service communication
Experience building and maintaining production React applications
Hands-on experience with AWS, including infrastructure as code using Terraform
Experience operating containerized workloads with Kubernetes and Docker in production
Experience designing and scaling microservice architectures, including service boundaries, versioning, and backward compatibility
Strong working knowledge of relational databases such as PostgreSQL or MySQL, including schema design and query performance, and caching layers such as Redis
Experience with CI/CD pipelines, automated testing strategies, and agile development practices
Experience building software in healthcare or another regulated domain, including familiarity with HIPAA, PHI handling, or software quality and validation requirements
Experience with observability and reliability tooling and improving system uptime
Experience mentoring engineers or leading small project teams
Demonstrated passion for designing and building practical, high-quality software and desire to add value to the team

Benefits

Comp & perks

Flexible work arrangement with the ability to work from GRAIL's office or from home
On-site engagement opportunities and activities at the Sunnyvale campus