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Core Competencies
Role fitCore Competencies
Use this summary to align your resume positioning with the role.
Demonstrates expertise in structural biology with a focus on model building, validation, and data analysis. Proficient in utilizing Python for analysis pipelines and evaluating structural representations while effectively communicating scientific reasoning and uncertainty.
Highest-signal resume keywords
PhD In Structural BiologyExpertise In X-Ray CrystallographyPython Analysis PipelinesHands-On Structural ExperienceDaily Use Of AI Agents
ATS Keywords
Tailor your resumeApplicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills
Model BuildingModel ValidationData AnalysisComputational Structural BiologyGeometry ComputationMap InterpretationFunctional InterpretationInteraction AnalysisMolecular DynamicsMetadynamics
Soft Skills
Judgment In Scientific ReasoningCommunication Of Uncertainty
Tools & Technologies
GemmiBiopythonBiotiteNumpyClaudeCursor
Industry Keywords
Structural BiologyBiophysicsBiochemistryCryo-EMNMRSAXSHDX-MSCross-LinkingAlphaFoldAI Reasoning
Tech Stack
Tools & technologiesAssemblyNumpyPythonRay
About the role
Key responsibilities & impact- Define expert reasoning and write gold-standard answers for structural biology questions
- Design realistic scenarios across data collection, processing, map interpretation, model building, validation, assembly, state assignment, comparison, functional interpretation, interaction analysis, molecular dynamics, and metadynamics
- Curate datasets spanning X-ray, cryo-EM, atomic models, AlphaFold, molecular dynamics, NMR, SAXS, HDX-MS, cross-linking, and SHAPE/DMS modalities
- Build Python analysis pipelines using gemmi, Biopython/biotite, and numpy
- Partner with software engineers to create benchmark workflows
- Test agents for artifacts, over-interpretation, incorrect interfaces, register shifts, mirrored maps, misdocked domains, and misuse of B-factors or occupancies
- Adjudicate ambiguous structural cases and identify evidence needed to resolve them
- Evaluate representations and comparisons, including biological assemblies, asymmetric units, reference states, and domain superposition
- Interrogate agent reasoning and challenge scientifically unsound conclusions
- Identify agent errors and explain expert alternatives
- Score agent confidence and reward appropriate uncertainty
Requirements
What you’ll need- PhD in structural biology, biophysics, biochemistry, or a related field
- Hands-on structural experience building and validating models
- Deep expertise in at least one area: X-ray crystallography, cryo-EM, NMR/solution methods, or computational structural biology
- Working fluency across the other structural biology methods
- Ability to compute contacts, superpositions, symmetry mates, map values, and geometry from files without a GUI
- Coding experience for structural data
- Daily use of Claude, Cursor, or similar AI agents
- Judgment to identify scientifically unsound AI reasoning
- Ability to calibrate confidence and communicate uncertainty
- US citizenship, permanent residency, or OPT-holder status
- No STEM OPT extension or sponsorship support
Benefits
Comp & perks- Guaranteed pay for weeks 1–4 while ramping
- Uncapped upside
- Full-time work on your own schedule
- Catered lunch and dinner daily for onsite employees
- Waterfront office in Mission Bay
- Monthly parking when available
- Company outings most months
- Team off-sites
- Latch run club, cycling, boxing, ice skating, and soccer
- Opportunity to move across teams
- Potential for rapid advancement into senior roles