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Leidos

Technical Lead

Leidos

. Lead the technical strategy, architecture, and implementation of AI-enabled solutions supporting cancer research, precision medicine, clinical research, and enterprise biomedical informatics .

Posted 9/29/2026full-timeUnited StatesSenior💰 $131,300 - $237,350 per yearWebsite

Core Competencies

Role fit
Core Competencies

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Demonstrates extensive expertise in AI and ML solutions, particularly in healthcare and biomedical research, with a strong focus on technical leadership, architecture, and compliance with Responsible AI standards. Proven ability to mentor multidisciplinary teams and effectively communicate with both technical and executive stakeholders.

Highest-signal resume keywords
AI Model DevelopmentMachine LearningDeep LearningBiomedical InformaticsCloud-Native AI Architectures

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills
Artificial IntelligenceMachine LearningDeep LearningNatural Language ProcessingComputer VisionPredictive AnalyticsGenerative AIData ScienceBiomedical InformaticsCloud Computing
Soft Skills
Analytical SkillsProblem-SolvingCustomer FocusCollaborationCommunication
Tools & Technologies
HPCAWSAzureGoogle Cloud PlatformKubernetesTensorFlowPyTorchScikit-learnMLflowKubeflow
Certifications & Qualifications
Public Trust / ADPII Clearance
Industry Keywords
Cancer ResearchPrecision MedicineClinical ResearchBiomedical ImagingGenomicsPrecision OncologyClinical TrialsTranslational ResearchNIH PoliciesNIST AI Risk Management Framework

Tech Stack

Tools & technologies
AWSAzureCloudCyber SecurityGoogle Cloud PlatformKubernetesPyTorchScikit-LearnTensorflow

About the role

Key responsibilities & impact
  • Lead the technical strategy, architecture, and implementation of AI-enabled solutions supporting cancer research, precision medicine, clinical research, and enterprise biomedical informatics
  • Serve as principal technical advisor to NCI leadership on AI, ML, biomedical informatics, and digital modernization initiatives
  • Partner with Government stakeholders, scientific leadership, and multidisciplinary SMEs to define technical priorities, evaluate emerging technologies, and deliver mission-focused solutions
  • Provide technical leadership across AI model development, deployment, and lifecycle management, including machine learning, deep learning, NLP, LLMs, computer vision, predictive analytics, and multi-agent AI systems
  • Oversee design and integration of AI capabilities for biomedical imaging, radiomics, genomics, multi-omics analysis, precision oncology, clinical trial optimization, semantic search, knowledge management, and decision support
  • Guide scalable AI and cloud-based architectures using HPC, AWS, Azure, Google Cloud Platform, Kubernetes, and modern MLOps practices
  • Ensure Responsible AI compliance, including model governance, explainability, bias mitigation, security, privacy, NIH policies, Executive Orders, and the NIST AI Risk Management Framework
  • Lead technical reviews, architecture discussions, executive briefings, and technology roadmaps
  • Mentor engineering teams and provide technical oversight to AI engineers, software developers, data scientists, cloud architects, cybersecurity specialists, and biomedical informatics SMEs
  • Evaluate and recommend emerging AI technologies to accelerate scientific discovery, improve operational efficiency, and advance NCI’s research mission

Requirements

What you’ll need
  • Master’s degree in Computer Science, Artificial Intelligence, Biomedical Informatics, Bioinformatics, Data Science, Computer Engineering, Applied Mathematics, or a related discipline
  • Minimum 15 years of progressively responsible technical leadership supporting large-scale Federal health, biomedical research, or scientific computing programs
  • Minimum 10 years designing, implementing, and leading enterprise AI and ML solutions within healthcare, biomedical research, life sciences or federal research environments
  • Demonstrated experience supporting NIH, NCI, or other Federal biomedical research organizations
  • Extensive expertise in deep learning, machine learning, generative AI, NLP, LLMs, computer vision, predictive analytics, biomedical informatics, and cloud-native AI architectures
  • Demonstrated experience advising executive Government customers on AI strategy, enterprise architecture, and digital modernization initiatives
  • Proven experience leading multidisciplinary teams consisting of AI engineers, data scientists, software engineers, cloud architects, cybersecurity specialists, and biomedical subject matter experts
  • Experience with HPC, cloud-native AI platforms, Kubernetes, DevSecOps, and MLOps
  • Familiarity with TensorFlow, PyTorch, Scikit-learn, Hugging Face, MLflow, Kubeflow, LangChain, vector databases, graph databases, and AI orchestration frameworks
  • Ability to obtain and maintain a Public Trust / ADPII Clearance
  • Ph.D. in AI, Biomedical Informatics, Computer Science, Computational Biology, or related field preferred
  • Experience supporting NCI organizations including CBIIT, CCR, DCTD, DCP, or related biomedical research programs
  • Experience with cancer informatics, biomedical imaging, radiomics, genomics, precision oncology, clinical trials, and translational research
  • Expertise with FHIR, OMOP, FAIR data principles, biomedical ontologies, semantic interoperability, and research data ecosystems
  • Strong customer focus and mission orientation
  • Excellent analytical and problem-solving skills
  • Ability to lead cross-functional teams in a collaborative environment
  • Commitment to quality, innovation, and continuous process improvement
  • Ability to communicate effectively with both technical and executive audiences