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Lighten

Commercial & Operations Manager – Life Sciences Partnerships

Lighten

. Work directly with the executive team and commercial team on pipeline, priorities, and cross-functional initiatives .

Posted 11/8/2026full-timeRemote • United StatesMid-LevelSeniorWebsite

Core Competencies

Role fit
Core Competencies

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Demonstrates expertise in client-facing roles within life sciences and healthcare, with strong capabilities in proposal writing, project management, and cross-functional collaboration. Proficient in translating complex clinical data into actionable insights while maintaining effective communication with senior stakeholders.

Highest-signal resume keywords
Client-Facing ExperienceProposal WritingProject ManagementLife Sciences KnowledgeCRM Tools Experience

ATS Keywords

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Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills
Proposal WritingProject ManagementData AnalysisClinical SpecificationsEpidemiologyBiostatisticsPublic HealthRFP ProcessesCohort DefinitionsEndpoint Analysis
Soft Skills
Excellent Written CommunicationExceptional OrganizationCuriositySelf-Starter MindsetStakeholder Management
Tools & Technologies
CRM ToolsEHR SystemsClaims Data
Industry Keywords
Life SciencesHealthcareHealth DataRWEHEORMedical AffairsClinical TrainingConsulting

About the role

Key responsibilities & impact
  • Work directly with the executive team and commercial team on pipeline, priorities, and cross-functional initiatives
  • Participate in customer calls with pharma and life sciences clients, capturing needs, following up, and helping move opportunities forward
  • Write and assemble proposals, scopes of work, and RFP responses communicating Lighten’s approach, deliverables, and value
  • Maintain accurate tracking of opportunity status, next steps, and deadlines across the pipeline, and flag risks early
  • Work with the clinical team to turn client requirements, including cohort definitions, endpoints, and data needs, into clear, actionable specifications
  • Relay clinical feedback back to the commercial team and client
  • Improve templates, processes, and internal playbooks so the commercial team can move faster and more consistently

Requirements

What you’ll need
  • 3-5 years of experience in a client-facing, operations, consulting, or analytical role, ideally in life sciences, healthcare, or health data/technology
  • Excellent written communication, with the ability to turn complex technical or clinical material into clear, persuasive proposals
  • Exceptional organization and follow-through, comfortable managing many moving pieces and deadlines at once
  • Comfort working with senior stakeholders, both internal executives and external clients
  • Curiosity and the ability to quickly learn clinical and data concepts well enough to bridge commercial and clinical teams
  • A self-starter mindset: you thrive in a fast-moving startup, take ownership, and figure things out without waiting to be told
  • Background in epidemiology, biostatistics, public health, other scientific fields, clinical/medical training or consulting
  • Working knowledge of EHR and claims data
  • Exposure to life sciences commercial, RWE, HEOR, or medical affairs organizations
  • Experience with CRM tools and proposal or RFP processes
  • Must be a resident of United States

Benefits

Comp & perks
  • Competitive salary
  • Employee equity options
  • 3% company-sponsored 401k contributions
  • Comprehensive medical, dental and vision insurance for employees and their families
  • Clear path into a sales role or a Chief of Staff role as you grow