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Madrigal Pharmaceuticals

Vice President, Global Medical Lead – MASH

Madrigal Pharmaceuticals

. Own the integrated global MASH medical plan and strategy across resmetirom and future MASH assets .

Posted 10/14/2026full-timeUnited StatesSenior💰 $359,234 - $431,273 per yearWebsite

Core Competencies

Role fit
Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates extensive leadership in Medical Affairs with a focus on developing and executing integrated medical strategies, evidence priorities, and stakeholder engagement. Possesses deep scientific understanding of MASH and related therapeutic areas, with a proven track record in managing complex, cross-functional teams.

Highest-signal resume keywords
MDLeadership Experience in Medical AffairsIntegrated Medical Strategy DevelopmentUS Launch ExperienceDeep Scientific Understanding of MASH

ATS Keywords

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Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills
Clinical ResearchOutcomes ResearchHealth PolicyHealth EconomicsEvidence Strategy DevelopmentStakeholder EngagementScientific CommunicationPortfolio ManagementMarket Access StrategyCross-Functional Team Leadership
Soft Skills
MentorshipCoachingTeam DevelopmentPsychological SafetyContinuous Improvement
Certifications & Qualifications
PhDMBA
Industry Keywords
Pharmaceutical IndustryBiotechnology IndustryMASHNAFLDNASHLiver FibrosisHepatologyGastroenterologyEndocrinologyMetabolic Disease

About the role

Key responsibilities & impact
  • Own the integrated global MASH medical plan and strategy across resmetirom and future MASH assets
  • Align priorities across evidence, stakeholder engagement, lifecycle planning, and intended outcomes with Medical Affairs leaders
  • Translate MASH medical strategy into actionable medical objectives with measurable outcomes
  • Incorporate market perspectives and adjust priorities and investments based on evidence, stakeholder needs, market dynamics, and portfolio opportunities
  • Make medical prioritization and tradeoff decisions across the MASH portfolio
  • Champion AI-enabled and innovative approaches to strategic planning and execution
  • Own the integrated evidence strategy and prioritize asset-level evidence priorities and areas of interest
  • Define evidence, scientific communication, congress, and engagement priorities
  • Integrate insights from Medical Affairs, R&D, Commercial, Market Access, Diagnostics, International teams, real-world practice, and external experts
  • Define stakeholder-specific engagement and communication priorities
  • Represent Medical Affairs on the Global Brand Team, program teams, Medical Leadership team, and lifecycle planning forums
  • Lead the end-to-end Medical strategy and cross-functional Medical Team for resmetirom
  • Serve as final escalation point and senior medical authority for complex scientific and medical issues
  • Synthesize portfolio progress, risks, opportunities, and tradeoffs for senior leadership
  • Serve as senior medical ambassador for MASH with external stakeholders worldwide
  • Represent Madrigal at scientific congresses, policy and clinical forums
  • Integrate the patient perspective into scientific strategy
  • Contribute to commercial planning for the MASH portfolio
  • Lead, develop, and retain a diverse team of Medical Directors
  • Set objectives, decision rights, performance expectations, and accountabilities across the Medical Director team
  • Provide mentorship, coaching, career development support, and performance oversight
  • Champion inclusion, psychological safety, scientific excellence, and continuous improvement

Requirements

What you’ll need
  • MD required
  • Advanced clinical training in hepatology, gastroenterology, endocrinology, internal medicine, metabolic disease, or a related field strongly preferred
  • PhD, MBA, or advanced training in clinical research, outcomes research, health policy, health economics, or business is a plus
  • Minimum of 15 years of progressive experience in the pharmaceutical or biotechnology industry
  • Substantial leadership experience within Medical Affairs at a global or senior regional level
  • Robust US launch experience required
  • Demonstrated success leading Medical Affairs strategy for a major asset or disease area across launch and post-launch optimization
  • Experience representing Medical Affairs on senior cross-functional asset, brand, development, or lifecycle teams
  • Strong experience developing integrated medical and evidence strategies
  • Deep scientific and clinical understanding of MASH, hepatology, metabolic disease, or a closely related therapeutic area
  • Direct experience in MASH, NAFLD/NASH, or liver fibrosis highly desirable
  • Track record of building, leading, and inspiring large, geographically dispersed, complex, global, cross-functional teams of scientific and medical professionals

Benefits

Comp & perks
  • Equity for all employees
  • Flexible paid time off
  • Medical insurance
  • Dental insurance
  • Vision insurance
  • Life/disability insurance
  • 401(k) traditional, Roth, and employer match offerings
  • Supplemental life insurance
  • Legal services
  • Mental health benefits through the Employee Assistance Program for employees and their family
  • Reasonable accommodations throughout the hiring process