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Vice President, Global Medical Lead – MASH
Madrigal Pharmaceuticals. Own the integrated global MASH medical plan and strategy across resmetirom and future MASH assets .
Core Competencies
Role fitCore Competencies
Use this summary to align your resume positioning with the role.
Demonstrates extensive leadership in Medical Affairs with a focus on developing and executing integrated medical strategies, evidence priorities, and stakeholder engagement. Possesses deep scientific understanding of MASH and related therapeutic areas, with a proven track record in managing complex, cross-functional teams.
Highest-signal resume keywords
MDLeadership Experience in Medical AffairsIntegrated Medical Strategy DevelopmentUS Launch ExperienceDeep Scientific Understanding of MASH
ATS Keywords
Tailor your resumeApplicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills
Clinical ResearchOutcomes ResearchHealth PolicyHealth EconomicsEvidence Strategy DevelopmentStakeholder EngagementScientific CommunicationPortfolio ManagementMarket Access StrategyCross-Functional Team Leadership
Soft Skills
MentorshipCoachingTeam DevelopmentPsychological SafetyContinuous Improvement
Certifications & Qualifications
PhDMBA
Industry Keywords
Pharmaceutical IndustryBiotechnology IndustryMASHNAFLDNASHLiver FibrosisHepatologyGastroenterologyEndocrinologyMetabolic Disease
About the role
Key responsibilities & impact- Own the integrated global MASH medical plan and strategy across resmetirom and future MASH assets
- Align priorities across evidence, stakeholder engagement, lifecycle planning, and intended outcomes with Medical Affairs leaders
- Translate MASH medical strategy into actionable medical objectives with measurable outcomes
- Incorporate market perspectives and adjust priorities and investments based on evidence, stakeholder needs, market dynamics, and portfolio opportunities
- Make medical prioritization and tradeoff decisions across the MASH portfolio
- Champion AI-enabled and innovative approaches to strategic planning and execution
- Own the integrated evidence strategy and prioritize asset-level evidence priorities and areas of interest
- Define evidence, scientific communication, congress, and engagement priorities
- Integrate insights from Medical Affairs, R&D, Commercial, Market Access, Diagnostics, International teams, real-world practice, and external experts
- Define stakeholder-specific engagement and communication priorities
- Represent Medical Affairs on the Global Brand Team, program teams, Medical Leadership team, and lifecycle planning forums
- Lead the end-to-end Medical strategy and cross-functional Medical Team for resmetirom
- Serve as final escalation point and senior medical authority for complex scientific and medical issues
- Synthesize portfolio progress, risks, opportunities, and tradeoffs for senior leadership
- Serve as senior medical ambassador for MASH with external stakeholders worldwide
- Represent Madrigal at scientific congresses, policy and clinical forums
- Integrate the patient perspective into scientific strategy
- Contribute to commercial planning for the MASH portfolio
- Lead, develop, and retain a diverse team of Medical Directors
- Set objectives, decision rights, performance expectations, and accountabilities across the Medical Director team
- Provide mentorship, coaching, career development support, and performance oversight
- Champion inclusion, psychological safety, scientific excellence, and continuous improvement
Requirements
What you’ll need- MD required
- Advanced clinical training in hepatology, gastroenterology, endocrinology, internal medicine, metabolic disease, or a related field strongly preferred
- PhD, MBA, or advanced training in clinical research, outcomes research, health policy, health economics, or business is a plus
- Minimum of 15 years of progressive experience in the pharmaceutical or biotechnology industry
- Substantial leadership experience within Medical Affairs at a global or senior regional level
- Robust US launch experience required
- Demonstrated success leading Medical Affairs strategy for a major asset or disease area across launch and post-launch optimization
- Experience representing Medical Affairs on senior cross-functional asset, brand, development, or lifecycle teams
- Strong experience developing integrated medical and evidence strategies
- Deep scientific and clinical understanding of MASH, hepatology, metabolic disease, or a closely related therapeutic area
- Direct experience in MASH, NAFLD/NASH, or liver fibrosis highly desirable
- Track record of building, leading, and inspiring large, geographically dispersed, complex, global, cross-functional teams of scientific and medical professionals
Benefits
Comp & perks- Equity for all employees
- Flexible paid time off
- Medical insurance
- Dental insurance
- Vision insurance
- Life/disability insurance
- 401(k) traditional, Roth, and employer match offerings
- Supplemental life insurance
- Legal services
- Mental health benefits through the Employee Assistance Program for employees and their family
- Reasonable accommodations throughout the hiring process