Principal Program Manager – Strategic Planning, Transformation

McKesson

. Lead development of multi-year strategic plans aligned to enterprise priorities, operating models, and financial targets .

Posted 10/8/2026full-timeIrving • Texas • United StatesLead💰 $170,100 - $283,500 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in strategic planning, financial management, and cross-functional initiative leadership, with a strong focus on driving business value and operational excellence. Proven ability to influence stakeholders and manage complex vendor relationships in a matrixed environment.

Highest-signal resume keywords

Strategic PlanningFinancial ManagementBusiness Case DevelopmentVendor Relationship ManagementChange Management

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Financial ModelingBudget ManagementROI MeasurementAnalytical Problem-SolvingInvestment Strategy Development

Soft Skills

Influencing Without AuthorityCommunicationFacilitation

Tools & Technologies

Lean Six SigmaAgileSAFeAWSAzure

Certifications & Qualifications

MBALean Six Sigma Black BeltPMPAgile/Scrum Certification

Industry Keywords

Digital TransformationHealthcareRegulated IndustriesEnterprise TechnologyLarge-Scale Business Transformation

Tech Stack

Tools & technologies

AWSAzurePMP

About the role

Key responsibilities & impact

Lead development of multi-year strategic plans aligned to enterprise priorities, operating models, and financial targets
Translate strategy into goals, success metrics, and execution roadmaps across portfolios and teams
Assess trends, risks, and opportunities to inform strategic decision-making
Develop business cases, investment strategies, and financial models
Drive execution of strategic initiatives across business, technology, finance, and operations
Establish governance, prioritization, and performance tracking for strategic programs and investments
Identify dependencies, risks, and tradeoffs and recommend mitigation strategies to senior leadership
Manage strategic investment portfolios, benefits realization, budgets, and expected business value in partnership with Finance
Oversee strategic vendor and partner relationships, including contract compliance, performance management, risk mitigation, and business alignment
Advise senior leaders and facilitate executive-level discussions, workshops, and planning forums
Communicate strategy and progress concisely and actionably
Provide recommendations balancing business outcomes, financial performance, operational capacity, and strategic risk
Champion disciplined planning, execution, and continuous improvement
Drive adoption of new ways of working, operating models, and governance structures
Support change management, communications, and capability-building for sustainable outcomes

Requirements

What you’ll need

Bachelor’s degree in Business, Strategy, Engineering, Finance, or a related field
10+ years of experience in strategy, management consulting, transformation, program leadership, or equivalent roles
Proven experience leading complex, cross-functional initiatives with executive visibility
Strong strategic planning, analytical, problem-solving, and financial management skills
Experience developing business cases, managing budgets, forecasting investments, tracking operational spend, and measuring ROI
Demonstrated financial acumen in investment decisions, portfolio tradeoffs, business value realization, and organizational financial objectives
Ability to influence without authority and operate effectively in a matrixed organization
Experience managing strategic vendors and partner relationships, including contract governance, performance management, negotiations, and service delivery oversight
MBA or equivalent preferred
Lean Six Sigma Black Belt and PMP or Agile/Scrum certification highly desirable
Experience with Lean Six Sigma Green Belt, SAFe, or technology/platform certifications such as AWS or Azure valuable
Experience in enterprise technology, digital transformation, operating model redesign, or large-scale business transformation preferred
Experience managing significant technology, consulting, or managed service vendor relationships and associated budgets preferred
Background in healthcare, regulated industries, or large-scale enterprises preferred

Benefits

Comp & perks

Competitive compensation package as part of McKesson’s Total Rewards
Annual bonus or long-term incentive opportunities may be offered
Benefits package (details provided via McKesson benefits information)
Equal employment opportunities
Reasonable accommodations for job search or employment application