Senior Director, NAPD Domain Architect

McKesson

. Lead architecture for McKesson's North American Pharmaceutical Distribution business .

Posted 10/8/2026full-timeIrving • Texas • United StatesSenior💰 $183,500 - $305,900 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates extensive expertise in Enterprise Architecture, including the development of strategies, governance frameworks, and roadmaps aligned with digital transformation objectives. Proven ability to lead architecture functions, manage teams, and influence senior executives in complex, regulated environments.

Highest-signal resume keywords

Enterprise Architecture Strategy DevelopmentDigital Transformation LeadershipAPI Architecture and IntegrationCloud-Native and Hybrid-Cloud EcosystemsStakeholder Management and Communication

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Enterprise ArchitectureSolution ArchitectureApplication ArchitectureDigital TransformationGovernance FrameworksCloud-Native DesignAPI DevelopmentMicroservicesData ArchitectureArchitecture Review Boards

Soft Skills

Strategic LeadershipTeam LeadershipStakeholder ManagementCommunicationOrganizational Change Leadership

Tools & Technologies

LeanIXArdoqMicrosoft AzurePower PlatformSAP Integration

Industry Keywords

Pharmaceutical DistributionSupply ChainOrder ManagementPricing PlatformsRegulated Environments

Tech Stack

Tools & technologies

AzureCloudDistributed SystemsMicroservices

About the role

Key responsibilities & impact

Lead architecture for McKesson's North American Pharmaceutical Distribution business
Build and lead the NAPD architecture function and own the end-to-end architecture landscape
Drive architecture decisions across Supply Chain Modernization, Pricing, Customer Performance Management, Sales Digital Tools, and Connect Ordering transformation programs
Develop architects and lead the NAPD architecture team, including hiring, succession planning, and performance management
Maintain current architecture landscape and estate-wide visibility across transformation programs
Identify portfolio-level duplication and rationalization opportunities before build
Lead the NAPD Architecture Community of Practice on patterns, standards, and shared design principles
Assess architecture quality and coherence across programs with enterprise and data architects
Define and execute NAPD architecture strategy aligned with digital transformation objectives
Deploy architecture standards, governance frameworks, decision rights, technology lifecycle management, and roadmaps with the Enterprise Architecture Board
Define API, integration, and interoperability strategies
Partner with executives and product leaders to prioritize investments and transformation programs
Manage architecture budget and resourcing
Develop and retain architecture talent while fostering engineering excellence and continuous improvement
Participate in executive presentations, architecture reviews, workshops, and strategic planning sessions

Requirements

What you’ll need

13+ years of professional experience in Enterprise Architecture, Solution Architecture, Application Architecture, or related strategic technology disciplines
6+ years of diversified leadership experience driving architectural direction, technology roadmaps, cross-functional alignment, organizational planning, and team leadership (or equivalent experience)
Bachelor's degree in Computer Science, Engineering, Information Systems, or related field
Experience leading enterprise-scale digital transformation programs across complex organizations
Expertise developing enterprise architecture strategies, governance frameworks, roadmaps, and reference architectures
Experience designing and modernizing cloud-native, hybrid-cloud, and platform-based enterprise ecosystems
Knowledge of enterprise integration, API architecture, microservices, and distributed systems
Experience influencing senior executives and driving organization-wide technology decisions
Strong communication, stakeholder management, and strategic leadership capabilities
Experience managing teams, budgets, roadmaps, and strategic technology investments
Experience building or maturing an architecture function and operating model
Limited travel may be required
Master's degree in Computer Science, Engineering, Business, or related discipline (preferred)
Domain experience in pharmaceutical distribution, supply chain, order management, or pricing platforms within complex, regulated environments (preferred)
Familiarity with LeanIX, Ardoq, or equivalent architecture landscape and portfolio tools (preferred)
Experience with Microsoft technology ecosystems, Azure cloud services, Power Platform, and enterprise platform engineering (preferred)
Experience integrating SAP platforms with enterprise applications (preferred)
Familiarity with AI and automation architectures (preferred)
Knowledge of enterprise data architecture, governance, analytics platforms, and advanced data management practices (preferred)
Experience operating within highly regulated environments (preferred)
Experience leading architecture review boards and technology governance councils (preferred)
Organizational change leadership (preferred)

Benefits

Comp & perks

Competitive compensation package
Annual bonus or long-term incentive opportunities may be offered
Hybrid or remote work arrangements may be available consistent with business requirements
Equal employment opportunities
Reasonable accommodation for job search or application