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MSD

Senior Director, Clinical Science – Atherosclerosis

MSD

. Provide strategic Clinical Science leadership across multiple atherosclerosis studies, programs, and assets .

Posted 10/17/2026full-timeUnited StatesSenior💰 $210,400 - $331,100 per yearWebsite

Core Competencies

Role fit
Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates advanced expertise in Clinical Science leadership, particularly in atherosclerosis studies, with a strong focus on clinical development strategy, regulatory compliance, and cross-functional collaboration. Proven ability to mentor and develop scientific talent while ensuring high-quality clinical data interpretation and strategic decision-making.

Highest-signal resume keywords
Clinical DevelopmentAtherosclerosis Therapeutic ExpertiseRegulatory CompliancePeople LeadershipClinical Research Management

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills
Clinical ScienceClinical Trial DesignData QualityMedical MonitoringTherapeutic KnowledgePortfolio Risk AssessmentEndpoint SelectionBiomarker StrategyClinical Data ReviewDisease Area Strategy
Soft Skills
Excellent CommunicationInfluenceExecutive Presentation SkillsCoachingMentoring
Certifications & Qualifications
Advanced Scientific Degree (PhD, PharmD, or Equivalent)Master’s Degree in Life Sciences
Industry Keywords
Pharmaceutical IndustryClinical Drug DevelopmentBiotechnologyEthical StandardsHigh Performance Team BuildingMatrix LeadershipCross-Functional TeamsHealth Authority InteractionsInspection ReadinessNew Technology Integration

About the role

Key responsibilities & impact
  • Provide strategic Clinical Science leadership across multiple atherosclerosis studies, programs, and assets
  • Contribute to disease area strategy, development planning, portfolio risk assessment, and scientific decision-making
  • Apply therapeutic expertise to study planning, data interpretation, issue resolution, endpoint selection, eligibility criteria, and biomarker strategy
  • Standardize Clinical Science approaches, medical data review practices, interpretation principles, and key deliverables
  • Promote scientific consistency across studies and programs while addressing program-specific needs
  • Guide interpretation of clinical data across studies, cohorts, and assets
  • Support portfolio discussions, governance reviews, senior leadership meetings, and management communications
  • Present cross-study insights, scientific assessments, and key issues to leaders and governance bodies
  • Translate portfolio priorities into Clinical Science strategies, capabilities, and resource plans
  • Manage and develop Directors, Principal Scientists, and Clinical Scientists as appropriate
  • Coach, mentor, provide feedback, and create development opportunities for Clinical Science talent
  • Partner with Clinical Operations, Regulatory Affairs, Biostatistics, Data Management, Drug Safety and Pharmacovigilance, Translational Medicine, Medical Affairs, and other functions
  • Represent Clinical Science in cross-functional planning and strategic decision-making forums
  • Ensure compliance with regulatory requirements, company policies, and established procedures
  • Support inspection readiness and documentation of Clinical Science contributions
  • Identify improvements to Clinical Science quality, consistency, and effectiveness

Requirements

What you’ll need
  • Advanced scientific or healthcare degree required (e.g., PhD, PharmD), or equivalent, with 8+ years of pharmaceutical, clinical drug development, and/or medical field experience preferred
  • OR Master’s degree, preferably in life sciences, and 12+ years of pharmaceutical, clinical drug development, and/or medical field experience
  • OR Bachelor’s degree, preferably in life sciences, and 15+ years of pharmaceutical, clinical drug development, and/or medical field experience
  • Significant experience in Clinical Development, Clinical Science, clinical drug development, or a related function within the pharmaceutical or biotechnology industry
  • Demonstrated Clinical Science leadership across multiple studies, programs, or assets
  • Deep atherosclerosis therapeutic expertise, including disease biology, treatment landscape, clinically relevant endpoints, and development considerations
  • Strong understanding of clinical trial design, clinical development strategy, clinical data review, and interpretation of oncology data
  • Experience contributing to disease area strategy, portfolio discussions, or cross-program planning
  • Experience contributing to regulatory submissions, safety reviews, or health authority interactions
  • Experience working effectively in cross-functional teams within a matrix environment
  • Ability to integrate information across studies and programs for scientific and business decisions
  • Excellent communication, influence, and executive presentation skills
  • Demonstrated people leadership, including management, coaching, and development of scientific staff
  • Required skills: Atherosclerosis, Clinical Development, Clinical Research Management, Clinical Sciences, Data Quality, Ethical Standards, High Performance Team Building, Matrix Leadership, Matrix Management, Medical Monitoring, New Technology Integration, People Leadership, Pharmaceutical Industry, Regulatory Compliance, Therapeutic Knowledge, Trial Design
  • No visa sponsorship

Benefits

Comp & perks
  • Annual bonus eligibility
  • Long-term incentive eligibility, if applicable
  • Medical, dental, and vision healthcare
  • Other insurance benefits for employee and family
  • Retirement benefits, including 401(k)
  • Paid holidays
  • Vacation
  • Compassionate days
  • Sick days
  • 25% travel requirements
  • Domestic relocation