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MSD

Senior Director, Clinical Science, Breast Oncology

MSD

. Provide strategic Clinical Science leadership across multiple breast oncology studies, programs, and assets .

Posted 10/21/2026full-timeUnited StatesSenior💰 $210,400 - $331,100 per yearWebsite

Core Competencies

Role fit
Core Competencies

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Demonstrates extensive expertise in Clinical Development and Clinical Science leadership, particularly in breast oncology, with a strong focus on clinical trial design, regulatory compliance, and cross-functional collaboration. Proven ability to mentor and develop scientific talent while driving strategic initiatives and ensuring high-quality scientific output.

Highest-signal resume keywords
Clinical DevelopmentClinical Research ManagementClinical Trial DesignPeople LeadershipTherapeutic Knowledge

ATS Keywords

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Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills
Clinical ScienceClinical Data ReviewStudy DesignOncology Data InterpretationDisease Area StrategyPortfolio Risk AssessmentScientific Decision-MakingEndpoint SelectionBiomarker StrategyRegulatory Submissions
Soft Skills
Excellent CommunicationInfluenceExecutive Presentation SkillsCoachingMentoring
Tools & Technologies
Visual AnalyticsAI-Enabled WorkflowsCentralized Data Review
Industry Keywords
Breast CancerClinical Drug DevelopmentPharmaceuticalBiotechnologyHealth Authority Interactions

About the role

Key responsibilities & impact
  • Provide strategic Clinical Science leadership across multiple breast oncology studies, programs, and assets
  • Contribute to disease area strategy, development planning, portfolio risk assessment, and scientific decision-making
  • Partner with Section Heads, Asset Leads, Program Development Team Leads, and cross-functional development teams
  • Guide study planning, protocol development, amendments, study design, endpoint selection, eligibility criteria, biomarker strategy, data interpretation, and issue resolution
  • Standardize Clinical Science approaches, medical data review practices, data interpretation principles, and key deliverables across the portfolio
  • Promote consistency and establish leading practices for Clinical Science work
  • Advocate for visual analytics, centralized data review, AI-enabled workflows, and other quality and efficiency improvements
  • Provide senior scientific guidance across assigned studies and programs
  • Identify and frame clinical, scientific, and data-related issues for cross-functional and governance discussions
  • Contribute to portfolio discussions, governance reviews, senior leadership meetings, program reviews, and management communications
  • Present cross-study insights, scientific assessments, and key issues to leaders and governance bodies
  • Translate portfolio priorities into Clinical Science strategies, capabilities, and resource plans
  • Directly manage Directors, Principal Scientists, and Clinical Scientists as appropriate
  • Set expectations for scientific quality, strategic thinking, collaboration, and communication
  • Coach, mentor, provide feedback, and develop Clinical Science talent
  • Foster accountability, inclusion, continuous learning, and strong team performance
  • Represent Clinical Science in cross-functional planning and strategic decision-making forums
  • Facilitate alignment across studies, programs, and functions
  • Ensure compliance with regulatory requirements, company policies, and established procedures
  • Support inspection readiness and appropriate documentation
  • Identify opportunities to improve Clinical Science quality, consistency, and effectiveness
  • Maintain awareness of scientific, clinical, and regulatory developments in breast oncology

Requirements

What you’ll need
  • Advanced scientific or healthcare degree required (e.g., PhD, PharmD), or equivalent, with 8+ years of pharmaceutical, clinical drug development, and/or medical field experience preferred; OR Master’s degree, preferably in life sciences, with 12+ years of experience; OR Bachelor’s degree, preferably in life sciences, with 15+ years of experience
  • Significant experience in Clinical Development, Clinical Science, clinical drug development, or a related pharmaceutical or biotechnology function
  • Demonstrated Clinical Science leadership across multiple studies, programs, or assets
  • Deep therapeutic area expertise in breast cancer, including disease biology, treatment landscape, clinically relevant endpoints, and scientific considerations affecting development
  • Strong understanding of clinical trial design, clinical development strategy, clinical data review, and oncology data interpretation
  • Experience contributing to disease area strategy, portfolio discussions, or cross-program planning
  • Experience contributing to regulatory submissions, safety reviews, or health authority interactions
  • Experience working effectively in cross-functional teams within a matrix environment
  • Ability to integrate information across studies and programs to support scientific and business decisions
  • Excellent communication, influence, and executive presentation skills
  • Demonstrated people leadership experience, including management, coaching, and development of scientific staff
  • Required skills: Clinical Development, Clinical Research, Clinical Research Management, Clinical Sciences, Clinical Trial Planning, People Leadership, Scientific Literacy, Study Design, Therapeutic Knowledge, Trial Design
  • No visa sponsorship
  • Must be a US and Puerto Rico resident
  • Valid driving license: No

Benefits

Comp & perks
  • Annual bonus and long-term incentive, if applicable
  • Medical, dental, vision healthcare and other insurance benefits for employee and family
  • Retirement benefits, including 401(k)
  • Paid holidays
  • Vacation
  • Compassionate and sick days
  • Hybrid work arrangement
  • 10% travel requirement
  • Relocation: No relocation