Senior Principal Scientist, Clinical Research – Breast Cancer

MSD

. Plan and direct clinical research activities involving new or marketed oncology medicines .

Posted 10/8/2026full-timeUnited StatesSenior💰 $282,200 - $444,200 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in clinical research management and drug development, with a strong focus on oncology and clinical trial design. Proven ability to collaborate with cross-functional teams and communicate scientific findings effectively.

Highest-signal resume keywords

Clinical Research ManagementOncology ResearchClinical Trial DevelopmentDrug DevelopmentClinical Medicine

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical ResearchClinical Trial DesignRegulatory ReportingInvestigational New Drug ApplicationsData AnalysisStudy MonitoringScientific WritingClinical Study ReportsTranslational ResearchResearch Methodologies

Soft Skills

Strong Interpersonal SkillsTeam CollaborationCommunication Skills

Certifications & Qualifications

M.D.M.D./Ph.D.Board Certified or Eligible in Oncology

Industry Keywords

Breast Cancer ResearchBiomedical ResearchClinical DevelopmentScientific ScholarshipClinical ScientistsCross-Functional Teamwork

About the role

Key responsibilities & impact

Plan and direct clinical research activities involving new or marketed oncology medicines
Manage the full clinical development cycle, including study design, placement, monitoring, analysis, regulatory reporting, and publication
Evaluate pre-clinical and translational work to generate early clinical development plans and Investigational New Drug applications
Develop clinical development strategies for investigational or marketed oncology drugs
Plan clinical trials, including design, operational plans, and settings
Monitor and manage ongoing or new clinical trials
Analyze and summarize clinical findings to support safety and efficacy decisions, new drug applications, clinical study reports, and publications
Participate in internal and joint internal/external research project teams
Supervise Clinical Scientists executing clinical studies
Collaborate with commercialization, regulatory affairs, statistics, and manufacturing experts on clinical development projects
Assist the Senior/Executive Director with study progress and scientific updates
Maintain awareness of scientific developments and research methodologies
Identify scientifically and operationally strong investigators
Establish communications with prominent clinical investigators
Attend scientific meetings
Author development documents, presentations, budgets, and position papers
Facilitate collaborations with external researchers around the world
Travel on company business approximately 20–25% of the time

Requirements

What you’ll need

M.D or M.D./Ph.D.
Experience in industry or as senior faculty in academia
Minimum of 3 years of clinical medicine experience
Minimum of 3 years of industry experience in drug development or biomedical research experience in academia
Demonstrated record of scientific scholarship and achievement
Proven track record in clinical medicine
Background in biomedical research
Strong interpersonal skills
Ability to function in a team environment
Breast Cancer Research
Clinical Medicine
Clinical Research
Clinical Research Management
Clinical Trial Development
Cross-Functional Teamwork
Drug Development
Oncology Research
Board Certified or Eligible in Oncology (and/or Hematology) (preferred)
Prior specific experience in clinical research and prior publication (preferred)
No visa sponsorship

Benefits

Comp & perks

Annual bonus
Long-term incentive, if applicable
Medical, dental, and vision healthcare
Other insurance benefits for employee and family
Retirement benefits, including 401(k)
Paid holidays
Vacation
Compassionate days
Sick days
Hybrid work arrangement