Principal Scientist, DDSAI, AI/ML

OneTrust

. Develop and benchmark novel agent architectures, reasoning strategies, and tool-use patterns for scientific research workflows .

Posted 10/2/2026full-timeUnited StatesLead💰 $117,000 - $201,250 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in developing and evaluating AI/ML systems, with a strong focus on Python and scientific computing. Capable of translating domain knowledge into innovative agent designs and contributing to impactful scientific research.

Highest-signal resume keywords

AI/ML System DesignPython ProficiencyRapid PrototypingLLM-Based SystemsAgile Programming Methodologies

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

AI/ML SystemsScientific Software DevelopmentExperimental DesignData ScienceAgent OrchestrationTool-CallingPrompt EngineeringRetrieval Augmented GenerationEvaluation FrameworksComputational Biology

Soft Skills

CollaborationIndependent WorkCommunication

Tools & Technologies

LangChainLangFuseAgile Methodologies

Certifications & Qualifications

Master's Degree in Computer ScienceMaster's Degree in Data ScienceMaster's Degree in Computational Biology

Industry Keywords

Drug DiscoveryClinical DevelopmentTranslational ScienceScientific Research WorkflowsPeer-Reviewed Publications

Tech Stack

Tools & technologies

Python

About the role

Key responsibilities & impact

Develop and benchmark novel agent architectures, reasoning strategies, and tool-use patterns for scientific research workflows
Prototype agentic capabilities across drug discovery, clinical development, and translational science
Rapidly iterate to identify approaches delivering genuine scientific value
Partner with therapeutic-area researchers to identify high-impact research problems
Translate domain expertise into concrete agent designs and experimental tool integrations
Publish findings through peer-reviewed papers, demonstrations, and knowledge-sharing
Establish patterns and reference implementations for moving successful innovations from experimentation into broader platforms
Define criteria for production readiness without owning ongoing operations
Contribute as an individual contributor and developing subject-matter expert in Data Science
Develop actionable insights, methods, and research for the internal Data Science community
Contribute to scientific projects, programs, and processes important to the Data Science function

Requirements

What you’ll need

Master's degree or higher in Computer Science, Data Science, Computational Biology, or a related discipline
Proven experience designing, building, and evaluating AI/ML systems or scientific software
Track record of moving from research prototype to demonstrated impact
Strong proficiency in Python and scientific computing
Experience with rapid prototyping, experimental design, and rigorous evaluation of AI capabilities
Hands-on experience with LLM-based systems and frameworks such as LangChain and LangFuse
Experience with agent orchestration, tool-calling, prompt engineering, retrieval augmented generation, and/or evaluation frameworks
Ability to work independently and within distributed developer teams using agile programming methodologies
Ability to collaborate across therapeutic-area scientists, data scientists, and engineers
Work authorization or other requirements applicable under U.S. federal, state, or local law

Benefits

Comp & perks

Consolidated retirement plan (pension)
Savings plan (401(k))
Long-term incentive program
Vacation – 120 hours per calendar year
Sick time – 40 hours per calendar year; 48 hours for Colorado residents; 56 hours for Washington residents
Holiday pay, including Floating Holidays – 13 days per calendar year
Work, Personal and Family Time – up to 40 hours per calendar year
Parental Leave – 480 hours within one year of birth/adoption/foster care of a child
Bereavement Leave – 240 hours for an immediate family member; 40 hours for an extended family member per calendar year
Caregiver Leave – 80 hours in a 52-week rolling period
Volunteer Leave – 32 hours per calendar year
Military Spouse Time-Off – 80 hours per calendar year
Hybrid work arrangement
Inclusive interview accommodations