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Queue

Lead Systems Engineer

Queue

. Define systems engineering processes, standards, tooling, and review practices across the company .

Posted 9/19/2026full-timeNewark • California • United StatesSeniorWebsite

Core Competencies

Role fit
Core Competencies

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Demonstrates deep expertise in system safety and architecture for autonomous systems, with a strong focus on regulatory compliance and risk management. Capable of influencing product strategy and technical direction while mentoring cross-disciplinary teams.

Highest-signal resume keywords
System Safety ExpertiseSOTIF Methods ApplicationHazard Analysis LeadershipRegulatory Strategy OwnershipSystem Architecture Design

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills
System SafetySOTIF (ISO 21448)Hazard Analysis (STPA, FMEA, FTA)System ArchitectureRequirements DefinitionInterface DesignQuantitative Trade StudiesData-Driven Decision MakingAutonomy/PerceptionEmbedded Software
Soft Skills
MentoringInfluencing Without AuthorityFirst-Principles ThinkingDecisiveness Under UncertaintyHigh Ownership
Tools & Technologies
Simulation ToolsTesting FrameworksField Data AnalysisSafety Monitoring Systems
Certifications & Qualifications
UL 4600ISO 26262IEC 61508ISO 14971IEC 62304ARP4754AARP4761
Industry Keywords
Autonomous SystemsPharmacy AutomationMedical DevicesAerospace SafetyRegulatory FrameworksSafety-Critical ProductsOperational ConsequencesEngineering Function Development

About the role

Key responsibilities & impact
  • Define systems engineering processes, standards, tooling, and review practices across the company
  • Own critical architectural decisions and set direction on margins, safety, and quality
  • Integrate hardware, software, autonomy, operations, and pharmacy teams
  • Mentor engineers across disciplines and grow systems thinking
  • Influence roadmap and product strategy alongside executive leadership
  • Define and own the system safety strategy for a fully autonomous pharmacy
  • Apply SOTIF methods to reduce risks from performance limitations, edge cases, and unknown-unsafe scenarios
  • Lead hazard analyses spanning perception, dispensing verification, software, and human interaction
  • Set safety metrics, acceptance criteria, and residual-risk arguments
  • Build safety evidence using simulation, testing, and field data
  • Establish safety monitoring and incident-learning loops as the fleet grows
  • Own regulatory strategy across state Boards of Pharmacy and relevant federal authorities
  • Translate regulator objectives into system requirements and verifiable evidence
  • Represent Queue’s engineering case with regulators, pharmacy partners, and standards bodies
  • Help shape emerging regulatory frameworks for pharmacy automation
  • Own system requirements, interfaces, and performance, reliability, and safety budgets
  • Build and maintain system-level models for throughput, reliability, safety, and cost
  • Drive quantitative trade studies and resolve ambiguity through first-principles analysis
  • Architect for scale, serviceability, and field reliability
  • Report to the Head of Systems Engineering with significant autonomy and influence

Requirements

What you’ll need
  • 8-12+ years of engineering experience on complex, safety-critical products, including senior technical leadership of system architecture or system safety
  • Track record of shipping systems with real safety, operational, and economic consequences
  • Direct robotics experience isn't required; experience may come from autonomous vehicles, aerospace, medical devices, or industrial automation
  • Deep expertise in system safety for autonomous or software-intensive systems, including SOTIF (ISO 21448) and hazard analysis methods (STPA, FMEA, FTA)
  • Experience building and defending safety cases or equivalent risk arguments with external stakeholders
  • Deep expertise in system architecture, requirements definition, interface design, and design trades
  • Fluency across hardware, software, and operations, with depth in at least one of: autonomy/perception, embedded or distributed software, electronics, or mechatronics
  • Demonstrated ability to set technical direction and influence without formal authority across teams and leadership
  • First-principles thinker who is data-driven, decisive under uncertainty, and operates with high ownership and low ego
  • Experience with autonomy and functional safety standards such as UL 4600, ISO 26262, IEC 61508, or ISO 10218
  • Experience with medical device or aerospace safety frameworks such as ISO 14971, IEC 62304, ARP4754A/ARP4761
  • Direct experience engaging regulators such as state agencies, NHTSA, FAA, FDA, DEA, or Boards of Pharmacy
  • Experience shaping standards, policy, or regulatory frameworks for emerging technology
  • Experience building an engineering function or processes at an early-stage company
  • Experience scaling autonomous systems from pilot to fleet deployment

Benefits

Comp & perks
  • Early-stage equity in automated pharmacy dispensing at scale
  • Direct impact — your work helps put medication safely in patients’ hands
  • Small team, zero bureaucracy, high trust
  • Health insurance
  • 401(k)
  • Unlimited PTO
  • Meaningful early-stage equity
  • High-visibility role with significant growth potential
  • Significant autonomy and influence
  • World-class team environment
  • Culture that prioritizes breakthrough thinking and rapid experimentation
  • Mission-driven team