Executive Director, Clinical Pharmacology/Pharmacometrics

. Lead clinical pharmacology and pharmacometrics strategy and execution for rare disease and oncology clinical programs .

Posted 9/25/2026full-timeRemote • United StatesLead💰 $261,800 - $314,600 per yearWebsite

Key responsibilities & impact

Lead clinical pharmacology and pharmacometrics strategy and execution for rare disease and oncology clinical programs
Develop clinical pharmacology and pharmacometric strategies supporting product development plans
Serve as Clinical Pharmacology lead for clinical development programs and representative for regulatory interactions
Perform and/or oversee modeling and simulation to solve drug development questions and expedite decision-making
Provide clinical pharmacology input on Phase 1–3 clinical studies and dedicated Phase 1 clinical pharmacology studies
Author and review clinical pharmacology sections of Investigator’s Brochures, INDs, NDAs, and other regulatory submissions
Act as clinical pharmacology expert during health authority interactions
Collaborate with clinical study, translational, preclinical, and due diligence teams
Work within Recursion’s Pharmacometrics team across Discovery and Development projects

What you’ll need

Ph.D. in Pharmaceutical Sciences, Pharmacokinetics or related discipline, M.D. with Clinical Pharmacology expertise, or Pharm.D. with a Clinical Pharmacology fellowship
10+ years of experience in biotech/pharmaceutical drug development
Demonstrated success leading all clinical pharmacology-related aspects of drug development
Experience managing PK, PK-PD, and PK-safety analyses, including non-compartmental analysis, population PK modeling, and PK-PD modeling and simulations
Proficiency with WinNonlin, Monolix, NONMEM, R, or other modeling software
Experience responding to regulatory agency questions, preparing clinical pharmacology aspects of regulatory submissions, and attending regulatory meetings
Ability to collaborate with internal and external stakeholders
Experience in oncology is preferred, but not required

Comp & perks