Executive Director, Global Site Management

Regeneron

. Provide enterprise-level strategic leadership and organizational accountability for global site-facing capabilities .

Posted 10/30/2026full-timeUnited StatesLead💰 $255,000 - $424,900 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates extensive expertise in global clinical operations, site management, and drug development, with a strong focus on strategic leadership, operational capabilities, and stakeholder engagement. Proven ability to lead high-performing teams and drive enterprise transformation across diverse therapeutic areas and regions.

Highest-signal resume keywords

Global Clinical Operations LeadershipDrug Development ExpertiseClinical Monitoring and Site ManagementExecutive Communication and InfluenceCross-Cultural Awareness

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Trial OperationsGCP CompliancePerformance ManagementResource and Budget PlanningRisk-Based Monitoring StrategiesVendor Relationship ManagementData Management OversightOperational Strategy DevelopmentSite Identification and SelectionPatient Recruitment and Retention

Soft Skills

Executive PresenceExceptional CommunicationNegotiation SkillsDecision-Making SkillsCollaborative Working Style

Industry Keywords

Global Site ManagementTherapeutic AreasClinical Development PlansEnterprise TransformationStakeholder Mobilization

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Provide enterprise-level strategic leadership and organizational accountability for global site-facing capabilities
Set the global vision and operating strategy for site management
Oversee monitoring execution, resource and budget planning, and CRO/FSP/vendor performance across the clinical development portfolio
Own the continued evolution of the global site management operating model
Partner with Therapeutic Area/Program Clinical Trial Management, Clinical Science, Quality, and Development Operations leadership to optimize portfolio performance
Advise senior and executive management and represent the function in key governance forums
Engage external vendors and collaboration partners at senior levels
Establish and advance the global strategy for country key opinion leader, investigator, and site relationships
Set direction and governance for global study execution, clinical site monitoring, and issue escalation
Sponsor risk-based, study-specific monitoring strategies and ensure consistent implementation and effectiveness
Define enterprise performance, quality, compliance, and productivity expectations
Champion standardization, digital enablement, innovation, and measurable value creation
Own the global workforce and capability strategy, including FTE and external-capacity forecasts, headcount planning, allocation, utilization, leadership development, and succession
Hold executive accountability for global vendor strategy, CRO/FSP contracting, investment, capacity, and performance
Lead senior-level vendor governance, commercial and operational decisions, and corrective interventions
Oversee country/site-level data and quality issues with study management, data management, Quality Management Leads, and other stakeholders
Partner with Global Monitoring Oversight, Central Monitoring, Vendor Relationship Management, and CRO counterparts
Serve as enterprise thought leader and senior subject matter authority for global site management
Influence internal strategy and external industry practice, sponsor cross-portfolio transformation, and build executive alignment for new capabilities and strategic investments
Establish the global CTL capability model, accountabilities, standards, and measures supporting study feasibility, site identification and selection, patient recruitment and retention, and complex investigator-site issue resolution

Requirements

What you’ll need

Minimum Bachelors Degree (Advanced Degree preferred)
17+ years of experience, including 10+ years of functional leadership and people management
Expert knowledge of drug development, global clinical operations, clinical monitoring, site management, GCP, and applicable regulations
Demonstrated ability to translate scientific and development strategy into scalable operational capabilities
Extensive experience leading global clinical trial operations and enterprise transformation across multiple therapeutic areas, regions, and development stages
Experience working with or establishing global clinical site relationships
Cross-cultural awareness and fluent Business English
Proven executive leadership in setting vision, leading through ambiguity, building high-performing global organizations, developing senior talent, shaping culture, and delivering sustained change at scale
Demonstrated success leading leaders and managing performance across global, matrixed, and partner-based organizations
Executive presence and exceptional communication, influence, negotiation, and decision-making skills
Ability to translate complex issues into clear enterprise choices and mobilize stakeholders to action
Excellent interpersonal skills and demonstrated collaborative as well as independent working style
Proactive and self-motivated
Ability to align activities with clinical development plans (CDPs)
Strong organizational skills with effective use of time and prioritization

Benefits

Comp & perks

Annual bonuses or other incentive plans
Equity awards
Pension or retirement benefits
401(k) company match
Health and wellness programs
Fitness centers
Medical, dental, vision, life and disability insurance benefits
Paid time off
Family support benefits
Reasonable accommodation during the recruitment process where required