Executive Director – Commercial & Medical Systems

Stoke Therapeutics

. Build and lead the technology foundation for Stoke’s first commercial launch.

Posted 11/9/2026full-timeBedford • Massachusetts • United StatesLead💰 $280,000 - $330,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates extensive experience in leading technology initiatives for commercial and medical systems within the biopharma sector, with a strong focus on Salesforce Life Sciences Cloud and regulatory compliance. Proven ability to manage multi-year program budgets, vendor relationships, and deliver high-quality data solutions for reporting and analytics.

Highest-signal resume keywords

Salesforce Life Sciences Cloud ImplementationCommercial Data Warehousing and AnalyticsRegulatory Compliance ManagementVendor and Budget ManagementExecutive-Level Communication

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

IT Systems ExperienceCommercial and Medical Affairs Technology LeadershipData Integration and ManagementIncident and Change ManagementPatient Services Hub DevelopmentContact Center Platform IntegrationAdverse Event ManagementDigital Engagement PlatformsMLR Review ProcessesAggregate Spend Reporting

Soft Skills

Strategic LeadershipHands-On Problem SolvingTeam CollaborationEffective CommunicationAdaptability in Fast-Paced Environments

Tools & Technologies

Salesforce CRMVeeva Vault PromoMatsCCaaS PlatformsIVR SystemsEnterprise Data Warehouse

Industry Keywords

BiopharmaLife SciencesHIPAA ComplianceTCPA RegulationsSample AccountabilityPatient Identification PlatformsRare Disease RegistriesPharmacy IntegrationsCommercial Systems GovernanceMarket Access Strategies

Tech Stack

Tools & technologies

CloudVault

About the role

Key responsibilities & impact

Build and lead the technology foundation for Stoke’s first commercial launch.
Report to the SVP & Chief Information Officer and lead Commercial & Medical Systems IT.
Own the commercial and medical launch stack and serve as the named IT partner to Commercial, Medical Affairs, Patient Services and Market Access.
Deliver the technology roadmap for the commercial and medical launch stack through the anticipated early-2028 launch.
Identify platform capabilities and enhancements and create a prioritized implementation roadmap.
Establish testing, training, support coverage, escalation paths and contingency plans; operate the live stack with ITIL-based incident, change and release management.
Partner with Technology Services on devices, access, training and field support for field hires.
Plan the post-launch Commercial & Medical Systems IT team and operating model.
Lead implementation and integration of Salesforce, MLR/content review, medical information, field enablement, advisory board, KOL engagement, speaker program, digital engagement and web platforms.
Deliver the patient services hub on Salesforce Life Sciences Cloud, including workflows and integrations with specialty pharmacy, benefits verification, copay and pharmacovigilance partners.
Implement a CCaaS platform for voice and text, IVR, routing, consent-managed recording and adverse-event routing.
Serve as accountable IT partner to Commercial Operations, Medical Affairs, Patient Services, Market Access, Trade & Distribution, Regulatory Advertising & Promotion and Corporate Communications.
Co-own the systems roadmap and governance through the Commercial IT steering committee.
Design the commercial and medical data foundation and integrations feeding the enterprise data warehouse.
Ensure complete, standardized, high-quality data for reporting, analytics and downstream applications.
Implement HIPAA, consent, recording retention, TCPA, sample accountability and SOX/ITGC controls, role-based access and SOPs.
Deliver aggregate spend and transparency reporting capabilities, including Open Payments and state-law reporting.
Manage the investment plan, business cases, platform evaluations, budget, vendors, licenses and renewals; report status, risks and decisions to the CIO and launch leadership.

Requirements

What you’ll need

Bachelor’s degree required; advanced degree a plus.
15+ years of IT or business systems experience in biopharma, including 8+ years leading commercial and/or medical affairs technology.
Has led the technology build for at least one pharmaceutical or biotech product launch.
Deep knowledge of life sciences commercial platforms, including Salesforce-based CRM, content management and MLR review, medical information and inquiry management, patient services hub programs, contact center platforms, field data and analytics, digital engagement and web/CMS platforms, and commercial data providers.
Strong understanding of the regulatory and compliance environment for commercial and medical systems, including HIPAA, consent management, promotional compliance, sample accountability and aggregate spend/transparency reporting.
Demonstrated success managing vendors, implementation partners and multi-year program budgets.
Executive-level communication skills.
Hands-on leader comfortable operating as both strategist and doer in a small, fast-moving team.
Experience implementing Salesforce Life Sciences Cloud or Health Cloud as an in-house patient services hub and integrating a contact center platform with Salesforce (preferred).
Experience with adverse event intake and handoff to pharmacovigilance from patient-facing systems (preferred).
Experience with Veeva Vault PromoMats for MLR review and medical information platforms such as MedComms or comparable tools (preferred).
Orphan or ultra-rare disease launch experience, including claims-based patient identification platforms, rare disease registries or specialty hub and pharmacy integrations (preferred).
Experience standing up commercial data warehousing and analytics (preferred).

Benefits

Comp & perks

Annual bonus
Equity participation
Medical insurance
Dental insurance
Vision insurance
Life insurance
Long- and short-term disability insurance
Paid parental leave
401K plan with company match
Unlimited vacation time
Tuition assistance
Employee Stock Purchase Program (ESPP)
Flexible work arrangements