Senior Medical Director

Summit Therapeutics, Inc.

. Provide medical affairs and clinical development leadership, including medical oversight of clinical studies .

Posted 10/14/2026full-timeRemote • United StatesSenior💰 $237,000 - $296,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in clinical development and medical affairs, particularly in hematology/oncology, with a strong focus on regulatory interactions, clinical trial execution, and cross-functional collaboration. Proficient in developing product strategies and communicating complex scientific information effectively.

Highest-signal resume keywords

MD Board CertificationHematology/Oncology Product Development ExperienceClinical Development Pathways KnowledgeClinical Trial Execution LeadershipFluent in English and European Languages

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical DevelopmentRegulatory InteractionsClinical Trial DesignAdverse Event MonitoringData AnalysisProtocol AdherenceSafety ReviewsClinical Study ReportsPublications DevelopmentOncology Treatment Expertise

Soft Skills

Clear CommunicationOrganizational SkillsCritical ThinkingProblem SolvingAttention to Detail

Tools & Technologies

MS Office SuiteElectronic Document Management SystemsDocument Review Tools

Certifications & Qualifications

Board Certified MD

Industry Keywords

Pharmaceutical R&DBiologicsBiotechFDAEMAClinical Development ProgramsBLA ApprovalsHematology/Oncology TherapeuticsClinical OperationsBiometrics

About the role

Key responsibilities & impact

Provide medical affairs and clinical development leadership, including medical oversight of clinical studies
Obtain scientific advisory input and work with external clinical investigators
Support regulatory interactions for product advancement
Collaborate with clinical operations on medical input and operational decision-making
Serve as a key medical expert for multiple cross-functional teams
Apply oncology treatment and management expertise to Summit medicines’ strategy and clinical development
Develop overall product strategy across multiple indications with Medical Affairs, Regulatory, Commercial, and other functions
Collaborate with Clinical Operations, Biometrics, Pharmacovigilance, and other functions to complete clinical development programs leading to BLA approvals
Lead clinical trial execution, clinical development strategy, and medical affairs planning
Contribute to product communications through publications, manuscripts, abstracts, posters, and scientific presentations
Contribute to two or more pivotal clinical development programs
Direct Phase 1–3 human clinical trials and help achieve development milestones and enrollment goals
Review adverse event reports and monitor safety data, evaluating and escalating safety signals
Coordinate information for reports submitted to FDA, EMA, PMDA, government, regulatory, or partner agencies
Present to regulators, governing and harmonization bodies, principal investigators, scientific conferences, advisors, and opinion leaders
Support clinical trial planning and execution, including protocol adherence, safety reviews, assay development, training, and clinical document review
Plan, review, and edit Clinical Study Reports
Plan, review, and edit program publications
Provide input on clinical study design supporting clinical strategy
Perform other duties as assigned

Requirements

What you’ll need

Board certified or eligible MD with hematology/oncology product development experience across stages of clinical development
Minimum of 5+ years’ experience in a pharmaceutical, biologics, or biotech R&D environment, or research environment involving collection and analysis of human data in hematology/oncology
Working knowledge of clinical development pathways for hematology/oncology therapeutics in the US and EMA
Fluent in English and at least one or more other European languages (French, Spanish, German, Italian, etc.)
Proficient user of standard MS Office suite, such as Word and Excel
Experience using electronic document management systems and document review tools desirable
Strong computer and database skills
Attention to detail, accuracy and confidentiality
Clear and concise oral and written communication skills
Excellent organizational skills
Critical thinking, problem solving, and ability to work independently
Ability to multitask and manage time-sensitive and highly confidential documents
Ability to communicate complex ideas clearly
Ability to prioritize conflicting demands
Ability to work in a fast-paced, demanding, and collaborative environment
Willingness and ability to travel for investigator engagement, face-to-face interaction, and protocol training

Benefits

Comp & perks

Potential bonus
Stock
Benefits
Variable compensation may be included in the total compensation package
Remote work arrangement