Clinical Trial Manager II

Syneos Health

. Provide site management oversight, clinical monitoring, and central monitoring deliverables focused on patient safety, protocol/GCP/regulatory compliance, and data integrity .

Posted 9/21/2026full-timeRemote • MexicoMid-LevelSeniorWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in clinical trial management, including site management, monitoring, and risk mitigation, while ensuring compliance with Good Clinical Practice and regulatory standards. Capable of leading teams and coordinating complex clinical activities across multiple trials or portfolios.

Highest-signal resume keywords

Site ManagementClinical MonitoringRisk-Based MonitoringGood Clinical PracticeBudget Management

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Trial ManagementRisk MitigationData IntegrityProtocol ComplianceMonitoring DocumentationClinical Monitoring PlansPerformance FeedbackProblem-Solving TechniquesCritical ThinkingFinancial Principles

Soft Skills

Conflict ResolutionTeam LeadershipCommunicationCoachingInterpersonal Skills

Tools & Technologies

CTMSDashboardsClinical Study ToolsUser Acceptance Testing

Certifications & Qualifications

Bachelor’s DegreeRN in a Related Field

Industry Keywords

Clinical TrialsRegulatory ComplianceInternational EnvironmentStudy ScopeInvestigator Payments

About the role

Key responsibilities & impact

Provide site management oversight, clinical monitoring, and central monitoring deliverables focused on patient safety, protocol/GCP/regulatory compliance, and data integrity
Oversee site interactions from activation through closeout, including recruitment and investigator payments
Identify clinical trial risks and develop risk mitigations
Review study scope, budget, protocol content, and contractual obligations
Monitor operational data, metrics, reports, timelines, quality, and budget risks
Participate in and present at key meetings, including Kick Off Meetings
Serve as an escalation point for investigator site communications and interact with principal investigators and site staff
Coordinate handoffs with Study Start Up, Patient Recruitment, and Data Management teams
Develop and maintain clinical study tools and templates, including Clinical Monitoring Plans
Ensure CTMS, dashboards, and other systems are configured and available, including user acceptance testing
Coordinate study-team training on protocols, CRFs, dashboards, SOPs, plans, data, and timelines
Oversee CRA and Central Monitor resourcing, site assignments, conduct, and delivery risks
Review monitoring documentation and ensure timely delivery to company and sponsor specifications
Provide clinical deliverable and risk status updates to clients, project management, and leadership
Support inspection readiness, corrective action plans, data cut, and database lock deadlines
Provide performance feedback to line managers
Coordinate clinical activities across complex trials or portfolios
Coach and mentor CTMs on clinical delivery, project risks, and action implementation

Requirements

What you’ll need

Bachelor’s degree or RN in a related field or equivalent combination of education, training, and experience
Demonstrated ability to lead and align teams in the achievement of project milestones
Demonstrated capability of working in an international environment
Demonstrated expertise in site management and monitoring (clinical or central)
Preferred experience with risk-based monitoring
Understanding of clinical trial management financial principles and budget management
Knowledge of Good Clinical Practice/ICH Guidelines and other applicable regulatory requirements
Good computer skills
Strong conflict resolution skills
Ability to apply problem-solving techniques to resolve complex issues and apply a risk management approach
Critical thinking to determine causes and appropriate solutions
Moderate travel may be required, approximately 20%

Benefits

Comp & perks

Career development and progression
Supportive and engaged line management
Technical and therapeutic area training
Peer recognition
Total rewards program
Inclusive culture
Reasonable accommodations when appropriate