Clinical Trial Manager II – Sponsor Dedicated

Syneos Health

. Provide site management oversight, clinical monitoring and central monitoring deliverables focused on patient safety, protocol/GCP/regulatory compliance and data integrity .

Posted 11/11/2026full-timeRemote • ChileMid-LevelSeniorWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in clinical site management and monitoring, ensuring compliance with Good Clinical Practice and regulatory requirements while effectively leading teams to achieve project milestones. Proficient in risk management and problem-solving techniques to address complex issues in clinical trial management.

Highest-signal resume keywords

Clinical Site ManagementRisk-Based MonitoringGood Clinical PracticeBudget ManagementProblem-Solving Techniques

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical MonitoringData IntegrityProtocol ComplianceRisk MitigationClinical Trial ManagementStudy Scope ReviewTraining CoordinationCorrective Action PlansSite Interaction OversightPerformance Feedback

Soft Skills

Communication SkillsInterpersonal SkillsConflict ResolutionCritical ThinkingTeam Leadership

Tools & Technologies

CTMSEDCEDiaryEPROsTMFIVRS/IWRSDashboardsClinical Monitoring PlanStudy ToolsAudit Trail Reviews

Industry Keywords

Clinical TrialsRegulatory ComplianceInternational EnvironmentProject MilestonesPatient Recruitment

About the role

Key responsibilities & impact

Provide site management oversight, clinical monitoring and central monitoring deliverables focused on patient safety, protocol/GCP/regulatory compliance and data integrity
Oversee site interactions from post-activation through site closeout, including patient recruitment and investigator payments
Identify critical data, process and protocol execution risks and develop risk mitigations
Review study scope of work, budget and protocol content and ensure clinical project teams understand contractual obligations and parameters
Identify and escalate risks to timelines, quality, budget and contracted scope
Participate in and present at key meetings, including Kick Off Meetings
Serve as an escalation point for investigator site staff communications and interact with principal investigators and site staff by phone or in person
Collaborate with Study Start Up, Patient Recruitment, Data Management and other functional leaders to meet study milestones
Develop and maintain clinical study tools and templates, including the Clinical Monitoring Plan
Ensure CTMS, dashboards and other systems are set up, available and properly maintained, including UAT and access/audit trail reviews
Coordinate initial and ongoing study-team training on protocols, CRF completion, dashboards, SOPs, plans, guidelines, data plans and timelines
Oversee CRA and Central Monitor resourcing, site assignments and study-team conduct
Ensure quality and visibility of clinical monitoring, central monitoring and site management deliverables
Review oversight dashboards and clinical trial systems including CTMS, EDC, eDiary, ePROs, TMF, IVRS/IWRS and central monitoring dashboards
Oversee compliance with monitoring strategies, CMP/SMP and risk plans
Review site and central monitoring documentation and ensure revisions, approvals and deadlines are completed
Interact with clients, project management, leadership and functional departments; provide status updates and solutions
Support inspection readiness for clinical trial management scope
Oversee CRAs and Central Monitors, assess compliance and identify emerging risks
Develop and support corrective action plans and activities to achieve data cut and lock deadlines
Provide staff performance feedback to line managers
May be assigned to larger, more complex trials

Requirements

What you’ll need

Bachelor’s degree or RN in a related field, or equivalent combination of education, training and experience
Demonstrated ability to lead and align teams in the achievement of project milestones
Demonstrated capability of working in an international environment
Demonstrated expertise in site management and monitoring (clinical or central)
Preferred experience with risk-based monitoring
Understanding of clinical trial management financial principles and budget management
Knowledge of Good Clinical Practice/ICH Guidelines and other applicable regulatory requirements
Good computer skills
Good communication, presentation and interpersonal skills among project team and with sites
Strong conflict resolution skills
Ability to apply problem-solving techniques to resolve complex issues and apply a risk-management approach
Critical thinking to determine causes and appropriate solutions
Moderate travel may be required, approximately 20%

Benefits

Comp & perks

Career development and progression
Supportive and engaged line management
Technical and therapeutic area training
Peer recognition
Total rewards program
Inclusive culture
Reasonable accommodations when appropriate