Executive Director, Clinical Development

Travere Therapeutics

. Lead overall clinical development strategy for assigned clinical trials .

Posted 10/21/2026full-timeSan Diego • California • United StatesLead💰 $246,000 - $332,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in clinical development strategy, particularly in nephrology and rare diseases, with a strong focus on clinical trial design, regulatory submissions, and cross-functional collaboration. Proven ability to lead multidisciplinary teams and engage with health authorities while managing complex clinical datasets and program risks.

Highest-signal resume keywords

Clinical Development StrategyNephrology ExpertiseRegulatory SubmissionsClinical Trial DesignLeadership in Clinical Research

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Trial DesignData InterpretationProtocol DevelopmentEndpoint StrategyBiomarker AnalysisStatistical ConsiderationsGlobal DevelopmentRegulatory InteractionsSafety AssessmentDose Selection

Soft Skills

Excellent Communication SkillsInterpersonal SkillsOrganizational SkillsCollaboration SkillsAbility to Multitask

Certifications & Qualifications

MDDO

Industry Keywords

NephrologyRare DiseasesClinical ResearchDrug DevelopmentHealth Authority InteractionsPediatric DevelopmentTranslational MedicinePrecision MedicineOrphan Renal DisordersMultinational Clinical Trials

About the role

Key responsibilities & impact

Lead overall clinical development strategy for assigned clinical trials
Contribute to indication strategy, target product profile, clinical positioning, and lifecycle planning
Design and oversee clinical studies across phases, including protocols, eligibility criteria, endpoints, dose selection, and statistical considerations
Provide leadership for study conduct, protocol deviation review, and data interpretation
Lead analysis and interpretation of clinical data
Author or review protocols, investigator brochures, clinical study reports, abstracts, manuscripts, and health authority briefing materials
Partner with Biometrics on analysis strategy and interpretation of efficacy, safety, PK/PD, and biomarker data
Serve as lead nephrologist for assigned development programs
Drive cross-functional alignment on program goals, timelines, risks, decision points, and resource needs
Lead clinical development discussions and represent Clinical Development at governance forums
Present integrated assessments, strategic options, and recommendations for decisions
Build integrated development plans and ensure execution against milestones
Identify program risks and develop mitigation strategies
Contribute to global regulatory strategy and represent Clinical Development in health authority interactions, including FDA and EMA
Prepare for and participate in IND, end-of-Phase 2, and other milestone regulatory meetings
Build relationships with academic experts, investigators, patient advocacy groups, and external nephrology and rare disease stakeholders
Support due diligence and business development activities involving external nephrology or rare disease assets
Partner with Clinical Operations on executable study designs and realistic enrollment strategies
Collaborate with Non-Clinical teams on mechanistic and disease-relevant endpoints
Interface with Clinical Pharmacology, Pharmacovigilance, CMC, HEOR, Medical Writing, and project functional leads
Align development plans with Medical Affairs, Commercial, and patient/community evidence-generation needs

Requirements

What you’ll need

MD, DO, or equivalent medical degree required
Advanced training in nephrology strongly preferred
Equivalent combination of education and applicable job experience may be considered
10+ years of relevant experience in clinical research or drug development required
At least 5 years in a leadership role responsible for clinical development strategy and major program decisions
Prior experience leading clinical programs in nephrology, rare disease, or closely related therapeutic areas strongly preferred
Strong understanding of clinical trial design, dose selection, safety assessment, endpoint strategy, and interpretation of complex clinical datasets
Experience with regulatory submissions and health authority interactions
Deep appreciation for the challenges of rare disease development, including small populations, site selection, natural history, endpoint selection, and patient engagement
Excellent communication and influence skills, with the ability to synthesize complex issues for senior leaders and governance bodies
Direct experience in rare kidney diseases, including inherited, glomerular, complement-mediated, or other orphan renal disorders
Experience with biomarkers, translational medicine, and precision medicine approaches relevant to renal disease
Experience in global development and multinational clinical trials
Familiarity with pediatric and adolescent development considerations in rare disease is desirable, depending on program scope
Strong interpersonal and organizational skills and excellent verbal and written communication skills
Ability to work effectively in a multidisciplinary team and foster respectful, open, and honest dialogue
Demonstrated ability to review, interpret, and present complex scientific data
Ability to multitask, prioritize, and manage shifting responsibilities in a dynamic, cross-functional environment
Excellent collaboration skills, attention to detail, and ability to manage complexity and challenges
Ability to adapt to changes in project plans and implement new strategies and tactics
Ability to travel domestically and internationally up to 20–25%

Benefits

Comp & perks

Premium health, financial, work-life and well-being offerings for eligible employees and dependents
Wellness and employee support programs
Life insurance
Disability insurance
Retirement plans with employer match
Generous paid time off
Short-term incentive
Long-term incentive compensation through company stock