Senior Director – Clinical Pharmacology

. Lead the technical and operational aspects of the Clinical Pharmacology department across preclinical and clinical development .

Posted 10/15/2026full-timeRemote • United StatesSenior💰 $235,500 - $329,500 per yearWebsite

Key responsibilities & impact

Lead the technical and operational aspects of the Clinical Pharmacology department across preclinical and clinical development
Oversee clinical pharmacology and translational PK/PD operations and deliverables across infectious disease and oncology programs
Serve as the clinical pharmacology and translational PK/PD technical expert on cross-functional project teams
Develop clinical pharmacology strategies supporting development and regulatory decisions from pre-IND through market authorization
Select and execute PK/PD, PopPK, and exposure-response modeling and simulation approaches for dose selection and optimization
Author and provide technical input for regulatory documents, submissions, and responses
Collaborate with clinical research, clinical operations, biomarkers, bioanalytical, biometrics, CMC, research, and regulatory teams
Establish and manage external vendor and collaborating-partner relationships
Generate and manage departmental budgets and optimize resource allocation
Manage, hire, mentor, and develop the Clinical Pharmacology and Translational PK/PD team
Report to the VP of Translational Development

What you’ll need

PhD, PharmD, or MD with relevant training in clinical pharmacology, pharmacokinetics, pharmaceutics, or related field
13+ years industry experience in Clinical Pharmacology, DMPK and/or related fields
Mastery of nonclinical and clinical pharmacokinetic concepts and methodologies
Deep understanding of multidisciplinary drug development requirements
Expertise in PK/PD, PopPK and exposure-response modeling
Extensive experience leading translational and clinical pharmacology work from candidate selection through market authorization
Strong understanding of regulatory requirements and experience contributing to regulatory submissions and engagements
Working knowledge of bioanalytical techniques supporting clinical development of small molecules and biologics
Experience with biologics, including monoclonal antibodies and bispecifics, required
Experience in oncology indications strongly preferred
Proficiency using standard PK analysis and graphing programs
Proven ability to manage and develop teams
Must currently be authorized to work for any employer in the U.S.; visa sponsorship is unavailable

Comp & perks