Senior Clinical Research Associate – CNS/Oncology

Worldwide Clinical Trials

. Lead site qualification, initiation, interim monitoring, management, and close-out activities in accordance with protocols, GCP, applicable regulations, and SOPs .

Posted 10/27/2026full-timeRemote • United KingdomSeniorWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in clinical research principles, GCP, and regulatory compliance while effectively leading and mentoring site teams. Proficient in managing clinical trial activities, ensuring patient safety, and maintaining data quality across multiple therapeutic areas.

Highest-signal resume keywords

Clinical Research Associate (CRA) ExperienceGood Clinical Practice (GCP)Regulatory ComplianceLeadership and Mentoring SkillsMicrosoft Office Proficiency

ATS Keywords

Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills

Clinical Research PrinciplesProtocol ComplianceMonitoring Plans DevelopmentData Quality AssuranceInvestigational Product AccountabilityTherapeutic Area ExpertiseTrial Master File DocumentationSource Documentation ReviewCRF ManagementFull-Service Monitoring

Soft Skills

Communication SkillsProblem-SolvingTeam ManagementPriority ManagementTraining and Development

Tools & Technologies

Microsoft OfficeIxRSEDC Systems

Industry Keywords

FDA RegulationsEU RegulationsICH GuidelinesSOPsClinical MonitoringPatient SafetyData Queries ResolutionSite ManagementInvestigational SitesClinical Trials

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Lead site qualification, initiation, interim monitoring, management, and close-out activities in accordance with protocols, GCP, applicable regulations, and SOPs
Protect patient safety and data quality by reviewing informed consent, safety information, source documentation, CRFs, and protocol compliance
Partner with investigators and site teams to resolve data queries and maintain regulatory and ethical documentation
Support the Investigator Site File and provide required documentation for the Trial Master File
Coordinate CRAs as a Lead CRA on global studies, working with Project Management to evaluate study milestones and deliverables
Mentor less experienced CRAs and site staff, including conducting accompanied visits, providing monitoring report feedback, and delivering study-specific training
Develop monitoring plans, tools, and templates and coordinate shipment and receipt of study materials
Ensure appropriate investigational product receipt, accountability, return, or destruction at assigned sites
Contribute clinical monitoring expertise to study team and investigator meetings, bid defenses, and development of protocols and CRFs
Travel to investigative sites approximately 8–10 days per month

Requirements

What you’ll need

MD or Pharmacy degree (MSPH, PharmD, PhD, or equivalent) with at least 3 years of CRA experience; OR a four-year degree in medical, biological, physical, health, pharmacy, or another related science with at least 5 years of CRA experience; OR a two-year college curriculum or equivalent education/training, preferably nursing or life sciences, with at least 7 years of CRA experience
Extensive knowledge of clinical research principles and processes, GCP, SOPs, FDA and/or EU regulations and directives, ICH Guidelines, and applicable local regulatory requirements
Strong therapeutic-area expertise across two to three therapeutic areas
Demonstrated leadership and communication skills, with the ability to mentor colleagues, guide site teams, solve problems, manage priorities, and contribute to monitoring and site-management process improvements
Proficiency with Microsoft Office, IxRS, and EDC systems
Experience in full-service monitoring preferred
A valid current passport and driving licence
Proficiency in spoken and written English
Must reside in the United Kingdom

Benefits

Comp & perks

Collaborative and inclusive environment
Growth and career development opportunities
Opportunity to learn and grow
Meaningful work improving patient lives through clinical research