Senior Clinical Trial Manager – Internal Medicine

Worldwide Clinical Trials

. Lead and provide direction to Clinical Research Associates and site management team members throughout the full study lifecycle .

Posted 11/6/2026full-timeRemote • North Carolina • United StatesSenior💰 $112,000 - $222,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in leading clinical research teams and managing clinical trials, with a strong focus on Internal Medicine studies. Proven ability to ensure high-quality study conduct through effective communication, operational oversight, and collaboration across cross-functional teams.

Highest-signal resume keywords

Clinical Trial ManagementClinical Operations LeadershipInternal Medicine Clinical TrialsTeam LeadershipProject Oversight

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Trial ManagementClinical ResearchSite ManagementMonitoring DeliverablesBudget ManagementStudy Lifecycle ManagementOut-of-Scope Activity ManagementCross-Functional CollaborationOperational OversightClinical Monitoring

Soft Skills

Effective CommunicationTeam MotivationLeadershipProblem SolvingCollaboration

Certifications & Qualifications

Bachelor’s DegreeNursing DegreeValid Passport

Industry Keywords

Clinical TrialsInternal MedicineCardio MetabolicRare DiseaseClinical Research Associate

About the role

Key responsibilities & impact

Lead and provide direction to Clinical Research Associates and site management team members throughout the full study lifecycle
Serve as the primary Site Management representative for clinical monitoring and site activities across assigned projects
Act as a key sponsor-facing contact and ensure effective communication throughout study execution
Oversee monitoring deliverables to support study objectives, quality expectations, and budget requirements
Identify and manage out-of-scope activities while communicating potential impacts and solutions
Drive collaboration across cross-functional teams to ensure consistent execution of clinical site management activities
Support high-quality study conduct through leadership, guidance, and operational oversight of project teams

Requirements

What you’ll need

Bachelor’s Degree or Nursing Degree
2+ years of experience as a Clinical Trial Manager, Clinical Operations Leader, Clinical Trial Lead, or equivalent role
4+ years of experience as a Clinical Research Associate
Ability to travel up to 25%
Valid passport required
Required experience supporting Internal Medicine clinical trials (IMID, Cardio Metabolic, Rare Disease)
Demonstrated ability to lead, motivate, and support remote teams

Benefits

Comp & perks

Competitive benefits package depending on location
Inclusive and equitable workplace
Growth and learning opportunities
Collaborative and inclusive work environment
Remote work arrangement