Principal Research Scientist I, Biologics CMC Developability Modeling

AbbVie

. Serve as a technical expert for modeling within the Biologics CMC Developability Team .

Posted 11/9/2026full-timeRemote • Illinois • United StatesLead💰 $124,500 - $236,500 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in mechanistic and statistical modeling techniques for protein stability and formulation screening, alongside strong technical writing and communication skills for scientific documentation and presentations.

Highest-signal resume keywords

Mechanistic Modeling TechniquesStatistical Modeling TechniquesPredictive Machine LearningTechnical WritingOral Communication Skills

ATS Keywords

Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills

Kinetic Degradation ModelingFeature AttributionSensitivity AnalysisModel InterpretabilityDeep LearningHierarchical FrameworksMulti-Task Frameworks

Soft Skills

Problem SolvingIndependenceAdaptabilityCollaboration

Industry Keywords

Biologics CMCPharmaceuticsPharmaceutical SciencesChemical EngineeringDevelopability Assessment

About the role

Key responsibilities & impact

Serve as a technical expert for modeling within the Biologics CMC Developability Team
Represent BCD in modeling communities within AbbVie and collaborate with modelers and other teams to ensure business needs are met by the correct modeling framework
Perform in vitro laboratory experiments as needed
Work with teams to design wet lab studies that build models and fundamental knowledge of protein solution behavior
Identify emerging scientific and technological trends from internal and external sources, assess relevance, and integrate applicable trends into BCD plans and strategies
Present data at internal and external professional conferences
Prepare manuscripts for publication in peer-reviewed journals or patent applications
Potentially serve as BCD Lead and coordinate developability assessment activities for 1–2 Discovery Projects at a time
Make cross-functional decisions across reporting lines

Requirements

What you’ll need

BS, MS, or PhD in Pharmaceutics, Pharmaceutical Sciences, Chemistry, Chemical Engineering, or related disciplines
14+ years of relevant industry experience with a bachelor's degree, 12+ years with a master's degree, or 6+ years with a PhD
Proven ability to solve critical scientific problems
Direct experience applying mechanistic or statistical modeling techniques to protein long-term stability or formulation screening, such as kinetic degradation modeling
Well versed in predictive machine learning and statistical modeling techniques
Familiarity with complex ML architectures including deep learning and hierarchical or multi-task frameworks
Skilled with feature attribution, sensitivity analysis, and model interpretability
Excellent oral communication skills in a scientific setting
Strong technical writing and documentation competencies
Ability to work independently, respond to changing priorities and short lead times for multiple tasks, identify problems, and work toward solutions

Benefits

Comp & perks

Paid time off (vacation, holidays, sick)
Medical, dental, and vision insurance
401(k)
Eligibility to participate in long-term incentive programs