Principal, Investments

American Cancer Society

. Lead the end-to-end investment process for prospective portfolio companies across therapeutics, diagnostics, and healthcare technologies, from sourcing through close .

Posted 10/21/2026full-timeRemote • United StatesLead💰 $175,000 - $200,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in leading the investment process within the biomedical and healthcare sectors, with a strong focus on health tech and digital health. Proven ability to conduct due diligence, develop investment theses, and mentor junior professionals while managing relationships with portfolio companies and stakeholders.

Highest-signal resume keywords

Venture Capital ExperienceInvestment Due DiligenceHealth Tech ExpertiseMentorship and LeadershipFinancial Modeling

ATS Keywords

Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills

Investment RecommendationsFinancial ModelingDue DiligenceInvestment Thesis DevelopmentPortfolio ManagementDeal SourcingMarket AnalysisPerformance MonitoringImpact InvestingVenture Philanthropy

Soft Skills

Strong Communication SkillsAttention to DetailMentoring AbilityRelationship DevelopmentTeam Leadership

Industry Keywords

Biomedical IndustryHealthcare TechnologiesDigital HealthLife Sciences InvestingCancer-Focused InnovationInvestment CommitteeScientific ConferencesInnovation TrendsEcosystem RelationshipsFundraising Strategy

About the role

Key responsibilities & impact

Lead the end-to-end investment process for prospective portfolio companies across therapeutics, diagnostics, and healthcare technologies, from sourcing through close
Conduct due diligence, financial modeling, and develop investment recommendations
Draft and deliver investment memos summarizing investment thesis, risk profile, and recommendation
Present directly to the BrightEdge team and Investment Committee and participate in Investment Committee discussions
Manage ongoing portfolio company relationships, including board observer responsibilities where applicable
Oversee quarterly and annual reporting and monitor company performance, strategy, and market developments
Develop investment views and proactive investment theses based on innovation trends and patient-centric unmet needs
Represent BrightEdge at scientific and medical conferences to identify emerging investment opportunities
Provide guidance, mentorship, and quality review to Associates and Senior Associates
Lead sourcing of investment opportunities and manage co-investor, venture partner, and ecosystem relationships
Support BrightEdge Innovation program applicant reviews and advise selected participants on scientific and fundraising strategy
Engage ACS researchers, research institutions, and advisory networks
Contribute to investor engagement, fundraising support, and external relationship development

Requirements

What you’ll need

Bachelor's degree required
At least 8 years of experience in venture capital and innovation (business development, external innovation, strategy consulting) in the biomedical/healthcare, health tech, or digital health industry (or equivalent)
Demonstrated investment/deal track record
Strong background in health tech, digital health, and/or life sciences investing
Ability to evaluate scientific, technical, and commercial merit across cancer-focused innovation
Proven investment experience in the biomedical/healthcare, health tech, or digital health industry
Demonstrated ability to lead deals from sourcing through close
Experience with and/or strong desire to learn impact investing and venture philanthropy
Strong oral and written communication skills
Excellent attention to detail
Demonstrated ability to lead, mentor, and develop junior investment professionals
Capacity to travel up to 25%
Regular travel to onsite meetings in Boston, MA required

Benefits

Comp & perks

Generous paid time off policy
Medical benefits
Dental benefits
Retirement benefits
Wellness programs
Professional development programs to enhance staff skills