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Biogen

Principal Analyst, Operations and Health Systems Research

Biogen

. Design, develop, and implement complex end-to-end data pipelines .

Posted 10/15/2026full-timeUnited StatesLeadWebsite

Tech Stack

Tools & technologies
NumpyPandasPySparkPythonPyTorchScikit-LearnTensorflow

About the role

Key responsibilities & impact
  • Design, develop, and implement complex end-to-end data pipelines
  • Engineer features and forecasting models to understand the intersection of health systems utilization and clinical research
  • Integrate real world data sources to build epidemiological and disease forecasting models supporting clinical trial operations decision-making
  • Leverage constraints-based optimization, linear and non-linear programming, simulation, and network modeling to understand participant, investigator, and sponsor behaviors driving risk, benefit, and uncertainty in clinical trial outcomes
  • Generate evidence and communicate results at conferences and in peer-reviewed publications for audiences in therapeutic areas, sensor science, machine learning, and operations research
  • Support integration, design, and development of novel measures, models, and metrics to assess model validity and performance across the model lifecycle

Requirements

What you’ll need
  • >= 5 years Pharma/Biotech/Tech/Healthcare industry experience, alternatively extensive experience in academic/clinical centers of excellence
  • Expertise in leveraging electronic health records and other data sources derived from clinical care via state-of-the-art methodologies, programming languages, and tools
  • Experience working on machine learning, operations research, and data science problems using formal software development lifecycle approaches and best practices as part of a software delivery organization
  • Profound experience in data science, machine learning, operations research, and data engineering programming using Python/R and higher-level libraries such as numpy, pandas, scipy, statsmodels, scikit-learn, Google OR Tools, TensorFlow/PyTorch, pyspark, tidyverse, sparklyr, mlr, tidymodels or similar
  • Strong familiarity with simulation and forecasting models used by business stakeholders and experience communicating results and improving models given feedback from end-users
  • Experienced in communicating and building consensus on highly technical or sensitive information with technology and business teams
  • Experience iterating through UI/UX patterns, data visualization, and front-end interactions and balancing across conflicting stakeholder preferences
  • Formal application of principles of empirical science including statistical modeling, design of experiments, and hypothesis formulation and testing
  • Advanced degree in public health, epidemiology, public health economics, operations research or a similar discipline

Benefits

Comp & perks
  • Regular employees are eligible for short-term and long-term incentives, including cash bonus and equity incentive opportunities
  • Medical, Dental, Vision, & Life insurances
  • Fitness & Wellness programs including a fitness reimbursement
  • Short- and Long-Term Disability insurance
  • A minimum of 15 days of paid vacation
  • Additional end-of-year shutdown time off (Dec 26-Dec 31)
  • Up to 12 company paid holidays
  • 3 paid days off for Personal Significance
  • 80 hours of sick time per calendar year
  • Paid Maternity and Parental Leave benefit
  • 401(k) program participation with company matched contributions
  • Employee stock purchase plan
  • Tuition reimbursement of up to $10,000 per calendar year
  • Employee Resource Groups participation