Principal Security Architect – Cybersecurity Engineering

City of Hope

. Define, develop, and maintain enterprise security architectures, engineering standards, technical patterns, and strategic roadmaps across identity, cloud, network, endpoint, infrastructure, application, and data security domains .

Posted 10/14/2026full-timeRemote • United StatesLead💰 $71 - $113 per hourWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in enterprise security architecture, including Zero Trust and microsegmentation, while providing technical leadership in cybersecurity engineering initiatives. Proficient in risk management practices and security automation across cloud environments, with a strong focus on compliance and regulatory standards.

Highest-signal resume keywords

Enterprise Security ArchitectureZero Trust ImplementationRisk Management PracticesCloud Security ArchitectureSecurity Automation

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Security ArchitectureSecurity EngineeringIdentity GovernancePrivileged Access ManagementContainer SecurityInfrastructure ProtectionThreat ModelingCybersecurity Technology Lifecycle ManagementDevSecOpsInfrastructure as Code

Soft Skills

Technical LeadershipMentoringIntegrityHonestyConfidentiality

Tools & Technologies

AzureAWSKubernetesSecurity Automation ToolsLogging and Monitoring Solutions

Certifications & Qualifications

CISSPCCSPSABSAMicrosoft Azure Security EngineerAWS Security Specialty

Industry Keywords

HealthcareLife SciencesRegulated IndustryCyber OperationsIncident Response

Tech Stack

Tools & technologies

AWSAzureCloudCyber SecurityIoTKubernetes

About the role

Key responsibilities & impact

Define, develop, and maintain enterprise security architectures, engineering standards, technical patterns, and strategic roadmaps across identity, cloud, network, endpoint, infrastructure, application, and data security domains
Lead the design and implementation of Zero Trust, microsegmentation, privileged access management, identity governance, cloud security, container security, security automation, and infrastructure protection capabilities
Provide technical leadership for security engineering initiatives, including platform selection, architecture reviews, proof-of-concept evaluations, integration planning, deployment strategies, and cybersecurity technology lifecycle management
Conduct architecture reviews, threat modeling, security assessments, and design consultations for enterprise projects, cloud migrations, application deployments, and emerging technologies
Establish engineering requirements for logging, monitoring, telemetry collection, security automation, orchestration, and Cyber Operations and Incident Response integration
Serve as senior cybersecurity engineering advisor to IT leadership, architects, engineers, and project teams
Develop technical standards, design documentation, architecture diagrams, and executive presentations
Mentor cybersecurity engineers and architects
Provide architectural guidance for secure adoption of AI, machine learning, cloud-native services, biomedical technologies, IoT, and emerging enterprise technology platforms
Follow established policies, procedures, objectives, performance improvement, attendance, safety, environmental, and infection control guidelines
Maintain confidentiality and perform other related duties as assigned or requested

Requirements

What you’ll need

Bachelor’s degree in Computer Science, Cybersecurity, Information Security, Management Information Systems, Computer Information Systems, Computer or Electrical Engineering, or a related field, or three additional years of relevant experience may substitute for the minimum education requirement
Nine years or more of progressive cybersecurity experience with significant depth in security architecture, security engineering, or both; or a master’s degree and seven years of relevant experience
Experience designing security controls across complex, multi-vendor enterprise environments
Experience applying risk analysis, risk assessment, and risk management practices
Preferred certifications: CISSP, CCSP, SABSA, Microsoft Azure Security Engineer, AWS Security Specialty, or equivalent advanced security architecture and engineering certifications
Preferred experience in enterprise cybersecurity engineering and architecture in healthcare, life sciences, or another highly regulated industry
Experience with Zero Trust architectures and microsegmentation programs
Cloud security architecture across Azure, AWS, and hybrid environments
Identity and access management, privileged access management, and identity governance solutions
Security automation, infrastructure as code, DevSecOps, container security, and Kubernetes security
Large-scale deployment and management of enterprise security platforms and controls
Adherence to City of Hope and department policies, procedures, objectives, safety, environmental, infection control guidelines, workplace Code of Conduct, and Compliance Plan
Integrity, honesty, and confidentiality

Benefits

Comp & perks

Comprehensive Benefits
Equal opportunity employment