Medical Director, US Medical Affairs

Cytokinetics

. Develop and execute the Medical Affairs strategy and US Plan of Action for aficamten .

Posted 10/7/2026full-timeUnited StatesLead💰 $276,120 - $322,140 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in Medical Affairs strategy, evidence generation, and hypertrophic cardiomyopathy, with a strong ability to engage healthcare professionals and manage medical programs effectively. Proficient in translating complex scientific information into actionable medical guidance while collaborating with cross-functional teams.

Highest-signal resume keywords

MD/DO Or PharmDMedical Affairs ExperienceCardiovascular TrainingProject Management SkillsKnowledge Of OPDP And PhRMA Code

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Medical Affairs StrategyEvidence GenerationClinical Trial Data EvaluationBiostatisticsEpidemiologyVendor ManagementBudget ManagementMedical Plan DevelopmentScientific CommunicationsReal-World Evidence

Soft Skills

Strong Oral CommunicationStrong Written CommunicationPresentation SkillsProfessionalismInterdisciplinary Team Collaboration

Tools & Technologies

Microsoft Office

Certifications & Qualifications

MD/DO Or PharmD

Industry Keywords

Hypertrophic CardiomyopathyPharmaceutical IndustryMedical Director ExperienceProduct LaunchCongress StrategyAdvisory BoardsMedical EducationClinical ResearchHealthcare Professional EngagementREMS Activities

About the role

Key responsibilities & impact

Develop and execute the Medical Affairs strategy and US Plan of Action for aficamten
Serve as medical and scientific expert for hypertrophic cardiomyopathy
Educate healthcare professionals on aficamten and its role in HCM therapy
Provide medical leadership across development, launch readiness, and lifecycle management
Execute medical launch activities and provide input into brand, evidence generation, market access, and lifecycle plans
Provide expertise for REMS activities
Partner with Clinical Development, Commercial, Regulatory, Safety, HEOR, Market Access, and Legal/Compliance teams
Plan scientific congresses, advisory boards, field force training, medical information responses, and related strategic projects
Collaborate with regional, global, and field medical colleagues on strategy, training, insights, and stakeholder engagement
Review hypertrophic cardiomyopathy medical education, grants, sponsorships, and promotional scientific materials via MLR
Manage medical programs, vendors, timelines, budgets, contracts, and performance measures
Respond to healthcare professional inquiries with clinical and scientific support
Develop integrated evidence plans and contribute to real-world evidence and investigator-sponsored research strategies
Analyze field medical insights to inform medical, evidence-generation, and educational strategies
Build and maintain a US hypertrophic cardiomyopathy key opinion leader network
Engage external experts in scientific exchange to address patient and medical-community needs

Requirements

What you’ll need

MD/DO or PharmD required
3-5 years of Medical Affairs experience required
Prior pharmaceutical industry and Medical Affairs Medical Director experience
Cardiovascular training and clinical experience strongly preferred
Knowledge of Medical Affairs strategy, evidence generation, scientific communications, and external engagement strongly preferred
Prior experience with product approvals, launch, and peri-launch activities highly desirable
Background in academic medicine and clinical research; familiarity with biostatistics and epidemiology highly desirable
Experience managing vendors, budgets, and strategic timelines a plus
Experience developing medical plans and aligning medical objectives with broader product and organizational strategy a plus
Familiarity with OPDP, PhRMA code, and key pharmaceutical industry regulations a plus
Ability to evaluate and interpret clinical trial data, peer-reviewed literature, treatment guidelines, and real-world evidence
Ability to work independently and as part of an integrated, interdisciplinary team
Ability to translate complex scientific information into clear, accurate, and actionable medical guidance
Strong project management skills, including managing multiple priorities, budgets, vendors, timelines, and deliverables
Working knowledge of congress strategy, advisory boards, medical education, and scientific communications
Strong oral, written, presentation, and executive communication skills
High scientific integrity, sound medical judgment, professionalism, and commitment to patient benefit
Proficiency with Microsoft Office
Ability to travel approximately 30% of the time

Benefits

Comp & perks

Equity in the form of stock options and/or restricted stock units
Comprehensive health, dental, vision, life and disability insurance coverage
401k retirement benefits with employer match
Learning and wellness stipends
Paid time off
Competitive total compensation package