Medical Director, US Medical Affairs

Cytokinetics

. Develop and execute the Medical Affairs strategy and US Plan of Action for aficamten .

Posted 10/30/2026full-timeRemote • United StatesLead💰 $276,120 - $322,140 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in Medical Affairs strategy, particularly in hypertrophic cardiomyopathy, with a strong focus on evidence generation, scientific communications, and stakeholder engagement. Proven ability to manage medical programs, budgets, and timelines while providing clinical and scientific support to healthcare professionals.

Highest-signal resume keywords

MD/DO Or PharmDMedical Affairs ExperienceCardiovascular TrainingProject Management SkillsKnowledge Of OPDP And PhRMA Code

ATS Keywords

Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills

Medical Affairs StrategyEvidence GenerationClinical Trial Data EvaluationMedical Plan DevelopmentVendor ManagementBudget ManagementScientific CommunicationsReal-World Evidence AnalysisHypertrophic Cardiomyopathy ExpertiseClinical Research Background

Soft Skills

Excellent Communication SkillsStrong Project ManagementAbility To Work IndependentlyInterdisciplinary Team CollaborationHigh Scientific Integrity

Tools & Technologies

Microsoft Office

Certifications & Qualifications

MD/DO Or PharmD

Industry Keywords

Hypertrophic CardiomyopathyPharmaceutical Industry RegulationsMedical LeadershipLaunch ReadinessField Medical AffairsCongress StrategyAdvisory BoardsMedical EducationREMS ActivitiesClinical Profile

About the role

Key responsibilities & impact

Develop and execute the Medical Affairs strategy and US Plan of Action for aficamten
Serve as medical and scientific expert for hypertrophic cardiomyopathy
Educate healthcare professionals on aficamten’s clinical profile and place in HCM therapy
Provide medical leadership through development, launch readiness, and lifecycle management
Execute medical launch activities
Provide medical input into brand, evidence generation, market access, and lifecycle management plans
Provide medical expertise for REMS activities
Partner with Clinical Development, Commercial, Regulatory, Safety, HEOR, Market Access, and Legal/Compliance teams
Plan scientific congress strategy, advisory boards, field-force training, medical information responses, and related strategic projects
Collaborate with regional, global, and US Field Medical Affairs colleagues
Support medical education, grant, and sponsorship review and evaluate initiative metrics
Manage medical programs, vendors, timelines, budgets, contracts, and performance measures
Respond to healthcare professional inquiries with clinical and scientific support
Review medical and promotional scientific materials through MLR
Contribute to integrated evidence planning, evidence-gap identification, real-world evidence, and investigator-sponsored research
Establish field medical scientific priorities, training plans, and stakeholder engagement strategy
Analyze field medical insights to inform medical, evidence-generation, and educational strategy
Support field material development and field medical education
Build and maintain a US hypertrophic cardiomyopathy key opinion leader network
Engage external hypertrophic cardiomyopathy experts in scientific exchange

Requirements

What you’ll need

MD/DO or PharmD required
3-5 years of Medical Affairs experience required
Prior pharmaceutical industry and Medical Affairs Medical Director experience
Cardiovascular training and clinical experience strongly preferred
Knowledge of Medical Affairs strategy, including evidence generation, scientific communications, and external engagement
Experience with product approvals, launch, and peri-launch activities highly desirable
Background in academic medicine and clinical research
Familiarity with biostatistics and epidemiology
Experience managing vendors, budgets, and strategic timelines
Experience developing medical plans and aligning medical objectives with broader product and organizational strategy
Familiarity with OPDP, PhRMA code, and key pharmaceutical industry regulations
Ability to evaluate and interpret clinical trial data, peer-reviewed literature, treatment guidelines, and real-world evidence
Ability to work independently and as part of an integrated, interdisciplinary team
Ability to translate complex scientific information into clear, accurate, and actionable medical guidance
Strong project management skills, including managing multiple priorities, budgets, vendors, timelines, and deliverables
Working knowledge of congress strategy, advisory boards, medical education, and scientific communications
Excellent oral, written, presentation, and executive communication skills
High scientific integrity, sound medical judgment, professionalism, and commitment to patient benefit
Proficiency with Microsoft Office
Ability to travel approximately 30% of the time

Benefits

Comp & perks

Equity in the form of stock options and/or restricted stock units
Comprehensive health, dental, vision, life and disability insurance coverage
401k retirement benefits with employer match
Learning stipends
Wellness stipends
Paid time off