Technical Manager – Manufacturing Applications

Danaher Corporation

. Own end-to-end management of GxP-regulated manufacturing systems, including lifecycle planning, enhancements, upgrades, rationalization, and decommissioning .

Posted 9/17/2026full-timeRemote • United StatesMid-LevelSenior💰 $95,000 - $140,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in managing GxP-regulated manufacturing systems, ensuring compliance with regulations and quality standards while overseeing system enhancements and operational stability. Proficient in coordinating validation processes, managing vendor relationships, and facilitating training for sustained compliance.

Highest-signal resume keywords

GxP-Regulated Systems ManagementManufacturing IT Systems SupportC# ProgrammingJavaScript/TypeScript DevelopmentMES, LIMS, QMS Expertise

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

GxP ComplianceValidation PlanningChange ControlIncident ManagementRoot Cause AnalysisSoftware DevelopmentSystem IntegrationsAutomationAPI-Based IntegrationsContinuous Improvement

Soft Skills

Team LeadershipCollaborationCommunicationProblem SolvingStakeholder Management

Tools & Technologies

Manufacturing Execution Systems (MES)Laboratory Information Management Systems (LIMS)Quality Management Systems (QMS)Modern Web FrameworksIT Service Management Tools

Industry Keywords

GxP RegulationsQuality StandardsInspection-ReadinessRegulated EnvironmentsDigital Transformation

Tech Stack

Tools & technologies

ITSMJavaScriptReactTypeScript

About the role

Key responsibilities & impact

Own end-to-end management of GxP-regulated manufacturing systems, including lifecycle planning, enhancements, upgrades, rationalization, and decommissioning
Ensure manufacturing systems comply with GxP regulations, internal quality standards, and inspection-readiness expectations
Coordinate validation planning, risk assessments, testing, documentation, change impact analysis, approvals, and deployments for GxP system changes
Partner with Quality, Manufacturing, and IT stakeholders to translate operational needs into compliant system capabilities and improvements
Oversee operational stability and performance, including incident management, root cause analysis, CAPAs, and continuous improvement
Manage vendors and service partners supporting GxP systems
Maintain inspection-ready documentation and support internal and external audits and regulatory inspections
Coordinate training and user enablement to ensure proper system use and sustained compliance
Report to the Director of Software Engineering as part of the IT Manufacturing Applications team

Requirements

What you’ll need

Bachelor’s degree in Information Technology, Engineering, Life Sciences, or a related discipline
At least 4 years of experience supporting or managing manufacturing IT systems in regulated environments
Experience with technically complex systems involving integrations, automation, or custom implementations
At least 1 year of supervisory, management, technical lead, or team lead experience
Strong understanding of manufacturing systems, such as MES, LIMS, QMS, instruments-related systems, or related manufacturing platforms
Experience operating within IT service management and quality governance processes
Hands-on software development experience supporting system integrations, automation, or platform enhancements
Experience using C#, JavaScript/TypeScript, modern web frameworks such as React, and API-based integrations
Experience supporting global or multi-site manufacturing environments is a plus
Exposure to manufacturing digital transformation initiatives is a plus
Demonstrated experience managing GxP-regulated systems, including validation support, compliance oversight, and change control, is a plus

Benefits

Comp & perks

Bonus/incentive pay eligibility
Paid time off
Medical insurance
Dental insurance
Vision insurance
401(k)