Senior Manager, Enterprise Cyber Defense

Dexcom

. Define and execute an Enterprise Cyber Defense strategy, operating model, and roadmap aligned to business risk, threat landscape, and Information Security priorities .

Posted 10/7/2026full-timeRemote • United StatesSenior💰 $181,000 - $301,600 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in defining and executing Enterprise Cyber Defense strategies, leading incident response efforts, and building high-performing cyber defense organizations. Proficient in detection engineering, threat hunting, and applying automation and AI to enhance security operations.

Highest-signal resume keywords

Cyber Defense StrategyDetection EngineeringIncident ResponseThreat HuntingCybersecurity Certifications

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

CybersecurityIncident ResponseDetection EngineeringThreat-Informed DefenseAdversary Behavior AnalysisAutomationAI in Security OperationsFrameworks such as MITRE ATT&CKRed/Purple TeamingCyber Readiness Exercises

Soft Skills

LeadershipCommunicationCross-Functional Team CollaborationDecision-MakingRisk Communication

Tools & Technologies

SIEMSOARXDREPPNDREmail SecurityIdentity TelemetryCloud Security

Certifications & Qualifications

CISSPCISMGIAC

Industry Keywords

Cyber DefenseThreat LandscapeIncident CommandCyber Readiness ProgramHigh-Severity Cyber Incidents

Tech Stack

Tools & technologies

CloudCyber Security

About the role

Key responsibilities & impact

Define and execute an Enterprise Cyber Defense strategy, operating model, and roadmap aligned to business risk, threat landscape, and Information Security priorities
Build and lead a high-performing global cyber defense organization across employees, contractors, and strategic service providers
Build and mature a threat-informed detection engineering lifecycle
Lead cyber response to emerging and non-traditional risk scenarios and evolving threats
Lead the agentic SOC and security automation strategy using AI-assisted triage and investigation with human-in-the-loop controls
Establish proactive threat hunting and adversary-validation capabilities
Own the cyber readiness program, including tabletop exercises, technical response simulations, playbook validation, escalation testing, and readiness assessments
Provide oversight and incident command for high-severity cyber incidents
Coordinate incident response across Security, IT, Privacy, Legal, business teams, and external partners
Translate lessons learned into improved detections, automation, controls, and response practices
Set strategy, architecture, integration, and optimization priorities for cyber defense platforms and telemetry
Define and report cyber defense KPIs and KRIs measuring detection coverage, response performance, false-positive reduction, automation and AI-agent performance, readiness, and risk reduction

Requirements

What you’ll need

BS/MS in Computer Science, Cybersecurity, Information Technology, Engineering, or a related field, or equivalent work experience
10+ years of experience in cybersecurity, IT, or engineering
5+ years focused on cyber defense, detection and response, or incident response
Proven success building, transforming, or scaling enterprise cyber defense capabilities
Strong experience in detection engineering, incident response, and threat-informed defense
Strong understanding of SIEM, SOAR, XDR, EPP, NDR, email security, identity telemetry, and cloud security
Deep knowledge of adversary behaviors, threat hunting, incident response, and detection methodologies
Practical use of frameworks such as MITRE ATT&CK
Experience with red/purple teaming or cyber readiness exercises strongly preferred
Experience applying automation, AI, or machine-learning capabilities to security operations
Ability to evaluate automated outputs, define performance measures, and maintain human oversight for security decisions
Ability to lead through high-severity incidents and ambiguous situations
Ability to communicate technical risk to executives and non-technical stakeholders
Ability to drive cross-functional teams toward timely decisions and outcomes
Strong background leading globally distributed technical teams and service providers
Certifications such as CISSP, CISM, GIAC, or other relevant cyber defense certifications may be included
Typically requires a Bachelor’s degree in a technical discipline with 13+ years of industry experience
5-8 years of previous people management experience
Ability to travel 5-15%

Benefits

Comp & perks

Medical, dental, and vision coverage
Wellness programs
Performance incentives
Opportunities for advancement
Flexible work arrangements
Unlimited paid time off
In-house training and development programs
Career mentorship
Opportunities to attend security conferences
Inclusive, diverse work environment
Home office workplace
Flex workplace option may be available for employees within commuting distance of a Dexcom site