Principal Scientist – ADME

Eli Lilly and Company

. Advance Lilly's ADME discovery portfolio through bioanalytical, drug-drug interaction (DDI), and project oversight activities .

Posted 10/8/2026full-timeIndianapolis • Massachusetts • United StatesLead💰 $69,000 - $195,800 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in bioanalytical studies, drug-drug interaction oversight, and vendor management within pharmaceutical operations. Proficient in project management and data quality assurance, with a strong focus on compliance and operational efficiency.

Highest-signal resume keywords

Bioanalytical Study OversightVendor ManagementProject Management Certification (PMP)LC-MS Bioanalytical PlatformsData Quality Assurance

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

BioanalysisDrug Metabolism and Pharmacokinetics (DMPK)ADME StudiesStudy Data ReviewBudget ManagementInvoice ReconciliationPerformance MonitoringProcess ImprovementScientific DocumentationCross-Functional Collaboration

Soft Skills

Problem-SolvingOrganizationFollow-ThroughWritten CommunicationVerbal Communication

Tools & Technologies

SmartsheetSciQuerySAP FioriAnalyst SoftwareWatson SoftwareAI ToolsWorkflow Automation

Certifications & Qualifications

Project Management Certification (PMP)

Industry Keywords

CRO OversightVendor RelationshipsOperational MetricsScientific ReviewsCompliance

Tech Stack

Tools & technologies

PMP

About the role

Key responsibilities & impact

Advance Lilly's ADME discovery portfolio through bioanalytical, drug-drug interaction (DDI), and project oversight activities
Lead bioanalytical and DDI studies with external research partners
Track study progress in Smartsheet and resolve issues
Manage study requests and vendor deliverables from intake through quality review
Review assay performance, data packages, deviations, and study reports for scientific and quality standards
Conduct annual scientific reviews of assigned vendors
Escalate technical or data-quality concerns and drive corrective action with scientists and quality teams
Ensure studies and contracts are delivered on time, within budget, and to scope
Reconcile vendor invoices and commitments against actual utilization
Report spend and operational metrics to stakeholders
Partner with quality, finance, project leadership, and internal scientific teams on vendor oversight and compliance
Apply approved AI and automation tools to improve data review, reporting, efficiency, and data quality
Support vendor governance, performance reviews, and contract renewals
Build vendor relationships and provide operational summaries and presentations to internal stakeholders

Requirements

What you’ll need

Bachelor's degree, preferably in a scientific field (e.g., chemistry, biochemistry, biology, pharmaceutical sciences)
7+ years of experience in a laboratory, CRO, or pharmaceutical operations setting, including vendor oversight
Experience reviewing bioanalytical, DMPK, or DDI study data and reports, and communicating concerns to vendors and internal partners
Advanced degree in a scientific field preferred
Experience in ADME, bioanalysis, or drug metabolism and pharmacokinetics (DMPK), including in vitro and in vivo study types preferred
Familiarity with LC-MS bioanalytical platforms and software, such as Analyst and Watson, and CRO data delivery workflows preferred
Experience with CRO oversight and sponsor-vendor interactions, including budget and invoice management, performance monitoring, and process improvement preferred
Project management certification, such as PMP, and demonstrated ability to manage multiple concurrent projects/programs to meet deliverable timelines preferred
Proficiency with SciQuery, SAP Fiori, and Smartsheet, and familiarity with RRL data loading and enterprise scientific data platforms preferred
Familiarity with AI and automation tools, such as generative AI assistants and workflow automation, preferred
Ability to produce high-quality written documentation including SOPs, job aids, reports, and executive-level summaries
Excellent problem-solving, organization, follow-through, written and verbal communication, and cross-functional collaboration skills
Up to 10% travel

Benefits

Comp & perks

Company bonus depending, in part, on company and individual performance
Company-sponsored 401(k)
Pension
Vacation benefits
Medical, dental, vision, and prescription drug benefits
Flexible benefits, including healthcare and/or dependent day care flexible spending accounts
Life insurance and death benefits
Certain time off and leave of absence benefits
Well-being benefits, including employee assistance program, fitness benefits, and employee clubs and activities
Employee resource groups and support networks