Senior Director, Portfolio Strategy, Analytics & Enablement

Eli Lilly and Company

. Lead portfolio-level strategy projects for Cardiometabolic Research from question framing through analysis, synthesis, and recommendation to the Core Leadership Team .

Posted 11/5/2026full-timeIndianapolis • United StatesSenior💰 $160,500 - $235,400 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in portfolio strategy and management within the pharmaceutical or biotechnology sectors, with a strong focus on cardiometabolic research. Proficient in developing metrics and dashboards to track strategic objectives and communicate effectively with diverse audiences.

Highest-signal resume keywords

Portfolio StrategyPortfolio ManagementMetrics And Dashboards DesignCross-Functional Project LeadershipCardiometabolic Disease Knowledge

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Portfolio AnalyticsRisk-Adjusted ValuationProbability Of Technical SuccessResource And Scenario ModelingDecision Analytics

Soft Skills

Clear CommunicationSynthesis Of Diverse OpinionsScientific Curiosity

Certifications & Qualifications

Advanced Degree (PhD, PharmD, MS, MBA)

Industry Keywords

Pharmaceutical R&DBiotechnologyCardiometabolic ResearchStrategic FramingOrganizational Communications

About the role

Key responsibilities & impact

Lead portfolio-level strategy projects for Cardiometabolic Research from question framing through analysis, synthesis, and recommendation to the Core Leadership Team
Assemble working teams, drive discussions, and deliver actionable outputs
Develop and maintain an integrated view of the portfolio across therapeutic pillars, development stage, therapeutic modality, target novelty, risk-reward profile, and resource load
Evaluate portfolio health and recommend improvements
Partner with therapeutic area leaders to maintain program strategies and learning plans
Surface shared scientific risks, resourcing conflicts, and unexplored white space
Translate strategic priorities into long-range plans, metrics, and dashboards
Own metrics and dashboards tracking progress against strategic objectives
Track competitive, scientific, and regulatory developments relevant to cardiometabolic research
Support organizational communications, including monthly updates to senior leadership and CMR-wide town halls
Drive program management and change management for CMR-wide capability initiatives
Manage recurring organizational processes and campaigns, including the President's Award proposal process
Communicate portfolio status and progress across the broader organization, including senior leadership

Requirements

What you’ll need

Bachelor's degree in a life science, quantitative, or business field
6+ years of experience in pharmaceutical or biotechnology R&D with roles involving portfolio strategy, portfolio management, decision analytics, or strategy consulting serving those functions
Experience leading cross-functional strategy projects from framing through to a leadership decision
Advanced degree (PhD, PharmD, MS, or MBA) preferred
Working knowledge of drug discovery and early development in cardiometabolic disease
Hands-on experience with portfolio analytics, including risk-adjusted valuation, probability of technical success, and resource and scenario modeling
Experience partnering with scientists on quantitative work while owning strategic framing
Track record of designing metrics and dashboards used by senior leaders
Ability to synthesize diverse opinions into actionable leadership recommendations
Clear written and spoken communication to scientific and non-scientific audiences, including governance committees
Scientific curiosity, enterprise mentality, and strong grasp of business concepts

Benefits

Comp & perks

Company bonus depending in part on company and individual performance
Company-sponsored 401(k)
Pension
Vacation benefits
Medical benefits
Dental benefits
Vision benefits
Prescription drug benefits
Healthcare flexible spending accounts
Dependent day care flexible spending accounts
Life insurance
Death benefits
Time off and leave of absence benefits
Employee assistance program
Fitness benefits
Employee clubs and activities
Employee resource groups (ERGs)