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Core Competencies
Role fitCore Competencies
Use this summary to align your resume positioning with the role.
Demonstrates expertise in hepatology, particularly in MASH and ALD, with a strong focus on translational science and biomarker strategies. Proven ability to lead cross-functional collaborations and drive scientific rigor in clinical development.
Highest-signal resume keywords
MD/PhD Or PhD In Cell Or Molecular BiologyExtensive Experience In Preclinical BiologyStrong Understanding Of Target MechanismsExperience Leading External CollaborationsProven Track Record Advancing Targets
ATS Keywords
Tailor your resumeApplicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills
Translational ScienceBiomarker StrategyTarget ValidationClinical Hypothesis SupportPharmacodynamicsPatient StratificationMechanistic RationaleDisease Activity AssessmentClinical Decision-MakingPortfolio Recommendations
Soft Skills
Scientific LeadershipMentorshipCommunication And PresentationInfluencing Decision-MakingManaging Multiple Priorities
Industry Keywords
HepatologyMASHALDCardiovascular DiseaseObesityPharmaceutical IndustryBiotechnologyTranslational EvidenceEthical StandardsQuality Expectations
About the role
Key responsibilities & impact- Provide scientific leadership across discovery and clinical-stage hepatology programs focused on MASH, ALD, and liver disease with cardiometabolic comorbidities
- Define human-relevant mechanistic hypotheses, target validation strategies, and translational plans
- Partner with technology, translational sciences, and disease-area experts to identify, validate, and advance therapeutic opportunities
- Lead biomarker strategies covering target engagement, pharmacodynamics, disease activity, patient stratification, and clinical decision-making
- Translate scientific and competitive trends into portfolio recommendations
- Influence cross-functional decision-making and align stakeholders on experiments, success criteria, translational strategies, and priorities
- Ensure scientific rigor, reproducibility, and fit-for-purpose model selection
- Provide mentorship and scientific guidance across the matrix
- Collaborate with biology, clinical development, translational medicine, biostatistics, DMPK, pathology, safety, and platform teams
- Translate preclinical and clinical datasets into insights for target selection, patient stratification, and study design
- Drive target progression and support clinical programs through integrated translational plans
- Champion innovative approaches, technologies, and model systems
- Establish and lead collaborations with academic institutions, CROs, biotechnology companies, and key opinion leaders
- Build and maintain an external expert network
- Contribute scientific leadership to business development evaluation and diligence
- Assess target biology, translational evidence, competitive differentiation, and portfolio fit
- Ensure compliance with policies, ethical standards, and quality expectations
- Help optimize portfolio investments and resource deployment
Requirements
What you’ll need- MD/PhD or PhD in cell or molecular biology, genetics, pharmacology, hepatology or a related discipline
- Extensive experience in preclinical biology and forward and reverse translation in liver disease
- Extensive pharmaceutical/biotechnology industry experience focused on hepatology therapeutics, including MASH and ALD
- Strong understanding of target mechanisms and translational evidence needed to support early clinical development
- Ability to operate as a senior individual contributor and scientific thought leader in a matrix environment
- Experience leading and managing external collaborations and business development diligence
- Proven track record advancing targets and/or assets through discovery and early development milestones
- Experience developing fit-for-purpose translational packages, including mechanistic rationale, human relevance, biomarker strategy, and clinical hypothesis support
- Strong knowledge of hepatology disease biology, pathways, mechanisms, MASH, ALD, cardiovascular disease, and obesity
- Preferred: translational science, business acumen, commercial aspects, communication and presentation, regulatory requirements, and managing multiple priorities
Benefits
Comp & perks- Competitive salary
- Annual bonus based on company performance
- Healthcare and wellbeing programmes
- Pension plan membership
- Shares and savings programme
- Hybrid working model balancing remote and in-office work
- Health care and other insurance benefits for employee and family
- Retirement benefits
- Paid holidays
- Vacation
- Paid caregiver/parental and medical leave
- Share-based long-term incentive program eligibility
- Reasonable and purposeful travel, including scientific conferences and occasional international collaboration meetings