Clinical Research Associate – Cross Therapeutic

ICON plc

. Serve as the primary point of contact between investigational sites and the sponsor .

Posted 9/21/2026full-timeRemote • Illinois • United StatesJuniorMid-Level💰 $91,336 - $114,170 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in site monitoring, compliance with ICH-GCP and local regulations, and proficiency in clinical systems such as CTMS and eTMF. Capable of managing site interactions, ensuring patient safety, and supporting recruitment efforts while maintaining high-quality data management.

Highest-signal resume keywords

Site Monitoring ExperienceICH-GCP ComplianceCTMS ProficiencyETMF ManagementLife Sciences Degree

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

On-Site MonitoringData EntryPatient Safety MonitoringSite SelectionRegulatory Compliance

Soft Skills

CommunicationCollaborationProblem-Solving

Tools & Technologies

CTMSETMF

Industry Keywords

Pharmaceutical IndustryCRO IndustryTherapeutic AreasSite ComplianceDrug Accountability

About the role

Key responsibilities & impact

Serve as the primary point of contact between investigational sites and the sponsor
Conduct site selection, initiation, routine monitoring, and close-out visits
Ensure site compliance with ICH-GCP, SOPs, and regulations
Maintain documentation in CTMS and eTMF systems
Support site staff training and compliance records
Monitor patient safety and AE/SAE/PQC reporting
Support subject recruitment and retention
Oversee drug accountability and storage, return, or destruction
Resolve data queries and drive timely, high-quality data entry
Document site progress and escalate risks or issues
Assist with site budgets and payments
Collaborate with CTAs, LTMs, and CTMs

Requirements

What you’ll need

Bachelor’s degree in Life Sciences or equivalent, or a qualified RN
Eligible to work in United States without visa sponsorship
2+ years of on-site monitoring experience in the pharmaceutical or CRO industry
Experience monitoring across multiple therapeutic areas
Proficient in ICH-GCP, local regulatory requirements, and clinical systems like CTMS and eTMF
Willing and able to travel up to 60% - 75% for on-site monitoring visits across midwest region
Preference given to candidates residing in Chicago near major HUB airports

Benefits

Comp & perks

Competitive base salary and performance related incentives
Health and wellbeing programmes including medical, dental, and vision coverage where applicable
Retirement and pension plans
Life assurance and disability coverage
Employee assistance programmes and wellbeing resources
Learning and development opportunities through structured training and career pathways