Lead Data Manager

ICON plc

. Lead end-to-end clinical data management start-up activities from protocol review through specification development, database build, testing, validation, and production go-live .

Posted 9/23/2026full-timeRemote • Spain, Poland, Bulgaria, United Kingdom, IrelandSeniorWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in clinical data management, including protocol review, database design, and compliance with CDISC standards. Proven ability to lead cross-functional teams and manage project timelines while ensuring data integrity and regulatory adherence.

Highest-signal resume keywords

Clinical Data ManagementProtocol ReviewCDISC StandardsData AnalysisProject Leadership

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Data AnalysisStatistical SoftwareData Visualization TechniquesECRF Design PrinciplesDatabase BuildTesting and ValidationDefect DocumentationSOP ComplianceICH-GCP ComplianceClinical Data Standards

Soft Skills

Analytical SkillsProblem-Solving SkillsCommunication SkillsLeadership SkillsCollaboration Skills

Tools & Technologies

ETMFSandbox TestingUser Acceptance Testing

Industry Keywords

Clinical ResearchData ManagementRegulatory RequirementsLife SciencesComputer Science

About the role

Key responsibilities & impact

Lead end-to-end clinical data management start-up activities from protocol review through specification development, database build, testing, validation, and production go-live
Review protocols to identify data collection requirements, build risks, inconsistencies, and impacts to database design or downstream processes
Translate protocol requirements into study build specifications, including visit schedules, assessments, eCRFs, dosing, data collection, and edit checks
Apply clinical data standards, including CDISC standards, eCRF design principles, field and variable conventions, and approved standard forms
Partner with the Standards team to implement protocol-specific modifications
Collaborate with Study Execution Teams, Medical Data Review, Programming, Data Management, Standards, and other stakeholders
Plan and oversee sandbox testing and user acceptance testing, including defect documentation, resolution, retesting, and system-readiness confirmation
Manage timelines, dependencies, deliverables, risks, and issue resolution for database go-live
Assess and manage the data management impact of protocol amendments and post-go-live changes
Maintain accurate data management start-up documentation in the eTMF
Ensure deliverables comply with SOPs, ICH-GCP, regulatory requirements, and internal quality standards
Manage day-to-day clinical data science activities and support team delivery

Requirements

What you’ll need

Bachelor's degree in life sciences, computer science, or a related discipline
Extensive experience in data analysis and project leadership within a clinical research setting
Strong expertise in statistical software and data visualization techniques
Exceptional analytical and problem-solving skills, with a focus on translating data into actionable insights
Excellent communication and leadership skills, with the ability to foster collaboration across diverse teams
Willingness to travel as required (approximately 15%)
Legal right to work in the country where the role is based

Benefits

Comp & perks

Competitive base salary and performance related incentives
Health and wellbeing programmes including medical, dental, and vision coverage where applicable
Retirement and pension plans
Life assurance and disability coverage
Employee assistance programmes and wellbeing resources
Learning and development opportunities through structured training and career pathways